FRG1

Gene Symbol FRG1
Entrez Gene 2483
Alt Symbol FRG1A, FSG1
Species Human
Gene Type protein-coding
Description FSHD region gene 1
Other Description FSHD region gene 1 protein|facioscapulohumeral muscular dystrophy region gene-1|protein FRG1
Swissprots Q14331 A8K775
Accessions AAD46768 EAX04600 Q14331 AA749391 AK291890 BAF84579 BC053997 AAH53997 BG426031 HQ448060 ADQ32541 L76159 AAA95939 XR_938715 XR_952267 NM_004477 NP_004468
Function Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N- methyltransferase SUV420H1. {ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:15060122, ECO:0000269|PubMed:20970242, ECO:0000269|PubMed:21699900, ECO:0000269|PubMed:23720823}.
Subcellular Location Nucleus, Cajal body. Nucleus, nucleolus. Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line. Note=Localization changes during myogenesis from mainly cytoplasmic in undifferentiated myoblasts, to strongly nucleolar in early myotubes and back to cytoplasmic 5 days post- differentiation. Localized at the Z-line in the sarcomere of matured myotubes 8 days post-differentiation.
Tissue Specificity Expressed in adult muscle, lymphocytes, fetal brain, muscle, and placenta. Also expressed in the smooth muscle of arteries and veins, the sweat glands and the epidermis. {ECO:0000269|PubMed:20970242}.

Human FRG1 full length protein - ab158466 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158466 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human FRG1 protein fragment - ab158467 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158467 on a 12.5% SDS-PAGE stained with Coomassie Blue.

FRG1 Antibody Blocking Peptide - LS-E4370 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FRG1 Antibody Blocking Peptide - LS-E19725 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FRG1 Antibody Blocking Peptide - LS-E19726 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

FRG1 Antibody Blocking Peptide - LS-E27326 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human FRG1 Protein - H00002483-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human FRG1 Protein - H00002483-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

FRG1-Antibody-C-term-Blocking-Peptide - BP16673b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

FRG1 blocking peptide - GTX88126-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Rat

FRG1 Peptide - AC21-2150-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

FRG1 - H00002483-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

FRG1 - H00002483-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

FRG1 - H00002483-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

FRG1 - H00002483-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

FRG1 Peptide - 42-552P from ProSci

Category Peptide
Species Human

FRG1 fusion protein - Ag6163 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human FRG1, His-tagged - FRG1-13002H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Protein FRG1(FRG1) - CSB-YP623915HU CSB-EP623915HU CSB-BP623915HU CSB-MP623915HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

FRG1 - TP308772 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
FRG1

FRG1, Peptide - MBS427260 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat

FRG1 Peptide, Human - M34GP05897H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Protein FRG1 (FRG1), Recombinant Protein - MBS1307086 from MyBioSource

Category Protein
Prices $1,010.00, $1,010.00, $1,240.00, $1,240.00, $1,550.00, $1,550.00, $2,015.00, $2,015.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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