FRG1

Gene Symbol FRG1
Entrez Gene 2483
Alt Symbol FRG1A, FSG1
Species Human
Gene Type protein-coding
Description FSHD region gene 1
Other Description FSHD region gene 1 protein|facioscapulohumeral muscular dystrophy region gene-1|protein FRG1
Swissprots Q14331 A8K775
Accessions AAD46768 EAX04600 Q14331 AA749391 AK291890 BAF84579 BC053997 AAH53997 BG426031 HQ448060 ADQ32541 L76159 AAA95939 XR_938715 XR_952267 NM_004477 NP_004468
Function Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N- methyltransferase SUV420H1. {ECO:0000269|PubMed:11991638, ECO:0000269|PubMed:15060122, ECO:0000269|PubMed:20970242, ECO:0000269|PubMed:21699900, ECO:0000269|PubMed:23720823}.
Subcellular Location Nucleus, Cajal body. Nucleus, nucleolus. Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line. Note=Localization changes during myogenesis from mainly cytoplasmic in undifferentiated myoblasts, to strongly nucleolar in early myotubes and back to cytoplasmic 5 days post- differentiation. Localized at the Z-line in the sarcomere of matured myotubes 8 days post-differentiation.
Tissue Specificity Expressed in adult muscle, lymphocytes, fetal brain, muscle, and placenta. Also expressed in the smooth muscle of arteries and veins, the sweat glands and the epidermis. {ECO:0000269|PubMed:20970242}.

FRG1 CRISPR/Cas9 KO Plasmid (h) - sc-417509 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 HDR Plasmid (h) - sc-417509-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 Double Nickase Plasmid (h) - sc-417509-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 Double Nickase Plasmid (h2) - sc-417509-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 CRISPR Activation Plasmid (h) - sc-417509-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 CRISPR Activation Plasmid (h2) - sc-417509-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 Lentiviral Activation Particles (h) - sc-417509-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 Lentiviral Activation Particles (h2) - sc-417509-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FRG1 siRNA (h) - sc-62350 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FRG1 shRNA Plasmid (h) - sc-62350-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FRG1 shRNA (h) Lentiviral Particles - sc-62350-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FRG1 RNAi - H00002483-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU148711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8936 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8936 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FRG1 siRNA (Human) - CRH1654 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FRG1 - MBS8239569 from MyBioSource

FRG1 - MBS8237783 from MyBioSource

shRNA set against Human FRG1(NM_004477.2) - SHH067997 from Creative biogene

Category siRNA
Species Reactivities Human

Human FRG1 siRNA - orb262156 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FRG1 shRNA Plasmid (Human) - CHH1654 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FRG1 miRNA 3'UTR clone - MiUTR1H-03847 from Creative biogene

Species Reactivities Human
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