FRG1

Gene Symbol	FRG1
Entrez Gene	2483
Alt Symbol	FRG1A, FSG1
Species	Human
Gene Type	protein-coding
Description	FSHD region gene 1
Other Description	FSHD region gene 1 protein\|facioscapulohumeral muscular dystrophy region gene-1\|protein FRG1
Swissprots	Q14331 A8K775
Accessions	AAD46768 EAX04600 Q14331 AA749391 AK291890 BAF84579 BC053997 AAH53997 BG426031 HQ448060 ADQ32541 L76159 AAA95939 XR_938715 XR_952267 NM_004477 NP_004468
Function	Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N- methyltransferase SUV420H1. {ECO:0000269\|PubMed:11991638, ECO:0000269\|PubMed:15060122, ECO:0000269\|PubMed:20970242, ECO:0000269\|PubMed:21699900, ECO:0000269\|PubMed:23720823}.
Subcellular Location	Nucleus, Cajal body. Nucleus, nucleolus. Cytoplasm. Cytoplasm, myofibril, sarcomere, Z line. Note=Localization changes during myogenesis from mainly cytoplasmic in undifferentiated myoblasts, to strongly nucleolar in early myotubes and back to cytoplasmic 5 days post- differentiation. Localized at the Z-line in the sarcomere of matured myotubes 8 days post-differentiation.
Tissue Specificity	Expressed in adult muscle, lymphocytes, fetal brain, muscle, and placenta. Also expressed in the smooth muscle of arteries and veins, the sweat glands and the epidermis. {ECO:0000269\|PubMed:20970242}.

FRG1 (C-5) - sc-377040 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

FRG1 (C-5): sc-377040. Western blot analysis of FRG1 expression in HeLa (A) and Jurkat (B) nuclear extracts.

FRG1 (FL-258) - sc-135066 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

FRG1 (FL-258): sc-135066. Western blot analysis of FRG1 expression in HeLa (A) and Jurkat (B) nuclear extracts.

FRG1 (N-19) - sc-54594 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

FRG1 (L-07) - sc-101050 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

FRG1 (L-07): sc-101050 Western blot analysis of FRG1 expression in human FRG1 transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-FRG1 antibody - ab55024 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-FRG1 antibody - ab171913 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-FRG1 antibody (ab171913) at 1 µg/mlLane 1 : FRG1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-rabbit HRP conjugated antibody at 1/7500 dilutiondeveloped using the ECL technique

Anti-FRG1 antibody - ab130334 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 antibody (ab130334) at 1/100 dilution + ZR-75-1 cell line lysates at 35 µg

Anti-FRG1 antibody [EPR13098] - ab181083 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR13098

All lanes : Anti-FRG1 antibody [EPR13098] (ab181083) at 1/10000 dilutionLane 1 : HeLa whole cell lysateLane 2 : Jurkat whole cell lysateLane 3 : 293 whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-FRG1 Antibody (clone 4A5) - LS-C197245 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4A5

Immunofluorescence of monoclonal antibody to FRG1 on HeLa cell. [antibody concentration 35 ug/ml]

Anti-FRG1 Antibody (aa230-256) - LS-C166252 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Western blot of lysates from HeLa, Jurkat cell line (from left to right), using FRG1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Anti-FRG1 Antibody (aa1-259, clone 10C273, Azide-free) - LS-C183632 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal
Clone	10C273

Anti-FRG1 Antibody (aa49-59) - LS-C112976 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

FRG1 antibody (2 ug/ml) staining of Jurkat nuclear lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-FRG1 Antibody (aa88-137) - LS-C135324 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

FRG1 antibody LS-C135324 Western blot of Rat Liver lysate.

Anti-FRG1 Antibody (aa230-256, Biotin) - LS-C207049 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody (aa230-256, AP) - LS-C207046 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody (aa230-256, APC) - LS-C207048 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody (aa230-256, FITC) - LS-C207050 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody (aa230-256, Azide-free, HRP) - LS-C207051 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody (aa230-256, PE) - LS-C207052 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody - LS-C310406 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody (aa229-257) - LS-C321461 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-FRG1 Antibody (aa118-167) - LS-C135325 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

FRG1 antibody LS-C135325 Western blot of Mouse Brain lysate.

FRG1 Antibody (4A5) - H00002483-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4A5

Western Blot: FRG1 Antibody (4A5) [H00002483-M01] - FRG1 monoclonal antibody (M01), clone 4A5 Analysis of FRG1 expression in Hela S3 NE.

FRG1 Antibody - NBP1-49864 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Western Blot: FRG1 Antibody [NBP1-49864] (2ug/ml) staining of Jurkat nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

FRG1 Antibody - H00002483-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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