Eng

Gene Symbol Eng
Entrez Gene 13805
Alt Symbol AI528660, AI662476, CD105, Endo, S-endoglin
Species Mouse
Gene Type protein-coding
Description endoglin
Other Description cell surface MJ7/18 antigen|transmembrane glycoprotein
Swissprots Q8K100 Q63961 Q61520
Accessions EDL08562 Q63961 AK018588 AK151302 BAE30285 AK164727 AK178235 AK178966 AK180986 AK183292 AK187426 AK187802 AK188120 AK196985 AK198539 AK199423 AY679531 AAT81170 BB851508 BC029080 AAH29080 BY226445 EU330531 ABY49139 S69407 AAB30196 X77952 CAA54917 XM_006497663 XP_006497726 XM_006497664 XP_006497727 NM_001146348 NP_001139820 NM_001146350 NP_001139822 NM_007932 NP_031958
Function Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells. {ECO:0000269|PubMed:23300529}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Endoglin is restricted to endothelial cells in all tissues except bone marrow and is also found in stromal cells within the connective tissue of intestine, stomach, heart, skeletal muscle, uterus, ovary, oviduct, testis and thymus.

Mouse ENG ORF clone(NM_001146348.1) - CDCL184038 from Creative Biomart

Species Mouse
Accession NM_001146348.1

Mouse Eng ORF Clone(NM_007932.2) - CDCL162358 from Creative Biomart

Species Mouse
Accession NM_007932.2

Mouse Eng ORF Clone(NM_001146348.1) - CDCL162359 from Creative Biomart

Species Mouse
Accession NM_001146348.1

Mouse Eng ORF Clone(NM_001146348.1) - CDCR238455 from Creative Biomart

Species Mouse
Accession NM_001146348.1

Mouse Eng ORF Clone(NM_001146350.1) - CDCR238458 from Creative Biomart

Species Mouse
Accession NM_001146350.1

Mouse Eng ORF Clone(NM_001146350.1) - CDCR238459 from Creative Biomart

Species Mouse
Accession NM_001146350.1

Mouse Eng ORF Clone(NM_007932.2) - CDCR244565 from Creative Biomart

Species Mouse
Accession NM_007932.2

Mouse Eng ORF Clone(NM_007932.2) - CDCR244566 from Creative Biomart

Species Mouse
Accession NM_007932.2

Mouse ENG ORF clone(NM_001146348.1) - CDCL184038 from Creative biogene

Species Mouse

Mouse Eng ORF Clone(NM_007932.2) - CDCR244566 from Creative biogene

Species Mouse

Mouse Eng ORF clone (NM_001146350.1) - CDCR060340 from Creative biogene

Species Mouse
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