Eng

Gene Symbol Eng
Entrez Gene 13805
Alt Symbol AI528660, AI662476, CD105, Endo, S-endoglin
Species Mouse
Gene Type protein-coding
Description endoglin
Other Description cell surface MJ7/18 antigen|transmembrane glycoprotein
Swissprots Q8K100 Q63961 Q61520
Accessions EDL08562 Q63961 AK018588 AK151302 BAE30285 AK164727 AK178235 AK178966 AK180986 AK183292 AK187426 AK187802 AK188120 AK196985 AK198539 AK199423 AY679531 AAT81170 BB851508 BC029080 AAH29080 BY226445 EU330531 ABY49139 S69407 AAB30196 X77952 CAA54917 XM_006497663 XP_006497726 XM_006497664 XP_006497727 NM_001146348 NP_001139820 NM_001146350 NP_001139822 NM_007932 NP_031958
Function Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells. {ECO:0000269|PubMed:23300529}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Endoglin is restricted to endothelial cells in all tissues except bone marrow and is also found in stromal cells within the connective tissue of intestine, stomach, heart, skeletal muscle, uterus, ovary, oviduct, testis and thymus.

Endoglin Antibody (Mouse Specific) - 3290 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from COS cells, untransfected or transfected with mouse endoglin, using Endoglin Antibody (Mouse Specific).

Endoglin (MJ7/18) - sc-18893 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Endoglin (MJ7/18) FITC: sc-18893 FITC. FCM analysis of mouse peripheral blood leukocytes. Quadrant markers were set based on the isotype control, normal rat IgG<sub>2a</sub>: sc-2831.

Endoglin (M-20) - sc-19793 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Endoglin (RM0030-6J9) - sc-101443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rat
Clonality Monoclonal
Endoglin (RM0030-6J9): sc-101443. Western blot analysis of Endoglin expression in non-transfected: sc-117752 (A) and mouse Endoglin transfected: sc-126793 (B) 293T whole cell lysates.

Endoglin (2Q1707) - sc-71042 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Endoglin (2Q1707): sc-71042. Western blot analysis of Endoglin expression in non-transfected: sc-117752 (A) and mouse Endoglin transfected: sc-126793 (B) 293T whole cell lysates.

Anti-CD105 antibody - ab21222 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD105 antibody (ab21222)Lane 1 : Recombinant mouse soluble CD105Lane 2 : Recombinant human soluble CD105

Anti-CD105 antibody [MJ7/18] - ab188488 from Abcam

Prices $372.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18

Anti-CD105 antibody [MJ7/18] - ab81456 from Abcam

Prices $372.00
Sizes 125 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18

Anti-CD105 antibody [MJ7/18] (Biotin) - ab95688 from Abcam

Prices $376.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18
Surface staining of bEND.3 cell line with 0.25 µg of ab95688 followed by Streptavidin PE. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

Anti-CD105 antibody [MJ7/18] (FITC) - ab114056 from Abcam

Prices $186.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18

Anti-CD105 antibody [MJ7/18] (Phycoerythrin) - ab93567 from Abcam

Prices $382.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18
Staining of bEnd.3 cells with 0.25 µg of PE Rat IgG2a Isotype Control (open histogram) or 0.25 µg of ab93567 (colored histogram). Total viable cells were used for analysis.

Anti-CD105 antibody [MJ718] (FITC) - ab184667 from Abcam

Prices $376.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone MJ718
Flow cytometry analysis of mouse endothelial cells labeling CD105. Upper panel: no primary antibody; Middle panel: solely conjugated secondary antibody; Lower panel: ab184667 at 5 µg/ml.

Endoglin/CD105 Antibody [Unconjugated] - AF1320 from Novus Biologicals

Prices $99.00, $365.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Endoglin/CD105 was detected in immersion fixed rat mesenchymal stem cells using Goat Anti-Mouse Endoglin/CD105 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1320) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Endoglin/CD105 Antibody (209701) [Unconjugated] - MAB1320 from Novus Biologicals

Prices $99.00, $269.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 209701
Endoglin/CD105 was detected in immersion fixed mouse mesenchymal stem cells using Rat Anti-Mouse Endoglin/CD105 Monoclonal Antibody (Catalog # MAB1320) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red; Catalog # NL013) and counterstained with DAPI (blue). Specific staining was localized to cytoplasmic. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Endoglin/CD105 Antibody (209721) - MAB13201 from Novus Biologicals

Prices $99.00, $269.00, $699.00
Sizes 25 µg, 100 µg, 500 µg
Host Rat
Clonality Monoclonal
Clone 209721

Endoglin/CD105 Antibody (MJ7/18) - NB100-77666 from Novus Biologicals

Prices $129.00, $299.00
Sizes 100 µg, 500 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18
Western Blot: Endoglin/CD105 Antibody (MJ7/18) [NB100-77666] - Total protein from mouse placenta was separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocking in 5% non-fat milk in TBST. The membrane was probed with 2 ug/ml anti-CD105 (NB100-77666) in 1% milk/TBST and detected with an anti-rat HRP conjugated secondary antibody using chemiluminescence.

Endoglin/CD105 Antibody (RM0030-6J9) - NB110-97870 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone RM0030-6J9
Immunohistochemistry-Paraffin: CD105 Antibody (RM0030-6J9) [NB110-97870] - Bouin's solution fixed and paraffin embedded normal mouse kidney section was subjected to immunohistochemistry staining (ABC) of CD105 using NB110-97870. Specific CD105 signal (DAB) is noted in vascular endothelial cells.

Endoglin/CD105 Antibody [Biotin] - BAF1320 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Endoglin/CD105 was detected in immersion fixed frozen sections of mouse lung using 15 µg/mL Goat Anti-Mouse Endoglin/CD105 Biotinylated Antigen Affinity-purified Poly­clonal Antibody (Catalog # BAF1320) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Endoglin/CD105 Antibody (209701) [Phycoerythrin] - FAB1320P from Novus Biologicals

Prices $229.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 209701
MS-1 mouse pancreatic islet endothelial cell line was stained with Rat Anti-Mouse Endoglin/CD105 PE-conjugated Monoclonal Antibody (Catalog # FAB1320P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Endoglin/CD105 Antibody (209701) [Fluorescein] - FAB1320F from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone 209701

Endoglin/CD105 Antibody (209701) [Allophycocyanin] - FAB1320A from Novus Biologicals

Prices $269.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 209701
MS-1 mouse pancreatic islet endothelial cell line was stained with Rat Anti-Mouse Endoglin/CD105 APC-conjugated Monoclonal Antibody (Catalog # FAB1320A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Endoglin/CD105 Antibody (MJ7/18) [DyLight 650] - NB100-77666C from Novus Biologicals

Prices $319.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18

Endoglin/CD105 Antibody (MJ7/18) [DyLight 488] - NB100-77666G from Novus Biologicals

Prices $319.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18

Endoglin/CD105 Antibody (MJ7/18) [DyLight 550] - NB100-77666R from Novus Biologicals

Prices $319.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone MJ7/18

Endoglin/CD105 Antibody (MJ7/18) [PerCP] - NB100-77666PCP from Novus Biologicals

Prices $579.00
Sizes 500 tests
Host Rat
Clonality Monoclonal
Clone MJ7/18
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