TFDP1

Gene Symbol TFDP1
Entrez Gene 7027
Alt Symbol DP1, DRTF1, Dp-1
Species Human
Gene Type protein-coding
Description transcription factor Dp-1
Other Description DRTF1-polypeptide 1|E2F dimerization partner 1|E2F-related transcription factor
Swissprots Q5JSB4 Q14186 B4DLQ9 Q8IZL5
Accessions AAN46090 EAX09216 EAX09217 EAX09218 EAX09219 Q14186 AK297114 BAG59621 AK298521 BAH12805 AK310401 AK313742 BC011685 AAH11685 BC036601 CD623680 DQ589756 DQ892865 ABM83791 DQ896114 ABM87113 L23959 AAA58440 XM_005268326 XP_005268383 XM_005268327 XP_005268384 XM_005268328 XP_005268385 XM_005268330 XP_005268387 XM_005268331 XP_005268388 XM_011537518 XP_011535820 XM_011537519 XP_011535821 XM_011537520 XP_011535822 NM_007111 NP_009042 NR_026580
Function Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000269|PubMed:20176812}.
Subcellular Location Nucleus.
Tissue Specificity Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
Top Pathways Cell cycle, TGF-beta signaling pathway

DP-1 (K-20) - sc-610 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DP-1 (K-20): sc-610. Western blot analysis of DP-1 expression in A-431 nuclear extract.

DP-1 (TFD-10) - sc-53642 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-1 (TFD-10): sc-53642. Western blot analysis of DP-1 expression in Daudi (A) and Raji (B) whole cell lysates and HeLa (C) nuclear extract.

DP-1 (TFD-11) - sc-56657 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-1 (TFD-11): sc-56657. Western blot analysis of DP-1 expression in HeLa (A) and Raji (B) whole cell lysates.

DP-1 (2Q471) - sc-70990 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-1 (2Q471): sc-70990. Western blot analysis of DP-1 expression in Raji whole cell lysate.

DP-1 (3F149) - sc-70989 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-1 (3F149): sc-70989. Western blot analysis of DP-1 expression in Daudi (A) and Raji (B) whole cell lysates.

DP-1/2 (H-67) - sc-292883 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

DP-1/2 (G-3) - sc-393398 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-1/2 (G-3): sc-393398. Western blot analysis of DP-1 expression in non-transfected 293T: sc-117752 (A), human DP-1 transfected 293T: sc-159192 (B), HeLa (C) and Raji (D) whole cell lysates and A-431 nuclear extract (E).

DP-1 (SPM178) - sc-56526 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-1 (SPM178): sc-56526. Western blot analysis of DP-1 expression in Raji (A) and HeLa (B) whole cell lysates.

DP-1/3 (A-16) - sc-16286 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DP-1/3 (A-16): sc-16286. Western blot analysis of DP-1/3 expression in C2C12 (A) and Daudi (B) whole cell lysates.

Anti-DP1 antibody - ab186831 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DP1 antibody (ab186831) at 1/500 dilutionLane 1 : K562 cell extractLane 2 : THP1 cell extractLane 3 : HeLa cell extract

Anti-DP1 antibody - ab44999 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DP1 antibody - ab127426 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DP1 antibody (ab127426)Lane 1 : Hela whole cell lysateLane 2 : Huvec whole cell lysateLane 3 : HepG2 whole cell lysate.Performed under reducing conditions.

Anti-DP1 antibody - ab52241 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DP1 antibody (ab52241) at 1/300 dilutionLane 1 : HeLa cell extract; without peptideLane 2 : HeLa cell extract; with peptide

Anti-DP1 antibody - ab90309 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DP1 antibody (ab90309) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µgSecondaryHRP conjugated anti-rabbit IgG at 1/50000 dilution

Anti-DP1 antibody [EPR4959(2)] - ab124678 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4959(2)
ab124678 at 1/10 dilution staining DP1 in permeabilized HeLa cells by Flow cytometry (red). Rabbit IgG negative control (green).

Anti-DP1 antibody [SPM178] - ab17807 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone SPM178
Human tonsil stained with anti-DP-1, (ab17807).

Anti-DP1 antibody [SPM178], prediluted - ab53924 from Abcam

Prices $370.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone SPM178
ab53924 (prediluted) staining DP1 in formalin fixed, paraffin embedded human tonsil tissue by Immunohistochemistry.

Anti-TFDP1 Antibody (clone 1DP06, Azide-free) - LS-C87449 from LifeSpan Bioscience

Prices $695.00, $1,085.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone 1DP06

Anti-TFDP1 Antibody (clone 1DP06) - LS-C87448 from LifeSpan Bioscience

Prices $295.00, $595.00, $1,015.00
Sizes 20 µg, 500 µl, 200 µg
Host Mouse
Clonality Monoclonal
Clone 1DP06
Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and AEC chromogen. Note nuclear and cytoplasmic staining of epithelial cells and lymphocytes.

Anti-TFDP1 Antibody (aa63-112) - LS-C29974 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFDP1 / Dp-1 antibody LS-C29974 was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.

Anti-TFDP1 Antibody (C-Terminus) - LS-C112313 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFDP1 / Dp-1 antibody LS-C112313 Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.

Anti-TFDP1 Antibody (C-Terminus) - LS-C112365 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFDP1 / Dp-1 antibody LS-C112365 Western blot of COLO205 cell lysate.

Anti-TFDP1 Antibody (clone SPM178) - LS-C189269 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone SPM178

Anti-TFDP1 Antibody (aa21-70) - LS-C135065 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFDP1 / Dp-1 antibody LS-C135065 Western blot of Mouse Liver lysate.

Anti-TFDP1 Antibody (aa361-410) - LS-C118433 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells, using DP-1 Antibody. The picture on the right is treated with the synthesized peptide.
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