TFDP1

Gene Symbol TFDP1
Entrez Gene 7027
Alt Symbol DP1, DRTF1, Dp-1
Species Human
Gene Type protein-coding
Description transcription factor Dp-1
Other Description DRTF1-polypeptide 1|E2F dimerization partner 1|E2F-related transcription factor
Swissprots Q5JSB4 Q14186 B4DLQ9 Q8IZL5
Accessions AAN46090 EAX09216 EAX09217 EAX09218 EAX09219 Q14186 AK297114 BAG59621 AK298521 BAH12805 AK310401 AK313742 BC011685 AAH11685 BC036601 CD623680 DQ589756 DQ892865 ABM83791 DQ896114 ABM87113 L23959 AAA58440 XM_005268326 XP_005268383 XM_005268327 XP_005268384 XM_005268328 XP_005268385 XM_005268330 XP_005268387 XM_005268331 XP_005268388 XM_011537518 XP_011535820 XM_011537519 XP_011535821 XM_011537520 XP_011535822 NM_007111 NP_009042 NR_026580
Function Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000269|PubMed:20176812}.
Subcellular Location Nucleus.
Tissue Specificity Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.
Top Pathways Cell cycle, TGF-beta signaling pathway

DP-1 CRISPR/Cas9 KO Plasmid (h) - sc-403331 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 HDR Plasmid (h) - sc-403331-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 Double Nickase Plasmid (h) - sc-403331-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 Double Nickase Plasmid (h2) - sc-403331-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 CRISPR Activation Plasmid (h) - sc-403331-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 CRISPR Activation Plasmid (h2) - sc-403331-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 Lentiviral Activation Particles (h) - sc-403331-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 Lentiviral Activation Particles (h2) - sc-403331-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-1 siRNA (h) - sc-37813 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DP-1 shRNA Plasmid (h)-SH - sc-37813-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DP-1 shRNA (h) Lentiviral Particles - sc-37813-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DP1 RNAi - H00007027-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU148581 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21254 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21254 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07496 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07496

TFDP1 siRNA (Human) - CRH4802 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFDP1 - MBS8225472 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human TFDP1 siRNA - orb265304 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFDP1 shRNA Plasmid (Human) - CHH4802 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TFDP1 miRNA 3'UTR clone - MiUTR3H-02239 from Creative biogene

Species Reactivities Human
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