ZBTB17

Gene Symbol ZBTB17
Entrez Gene 7709
Alt Symbol MIZ-1, ZNF151, ZNF60, pHZ-67
Species Human
Gene Type protein-coding
Description zinc finger and BTB domain containing 17
Other Description Myc-interacting Zn finger protein-1|zinc finger and BTB domain-containing protein 17|zinc finger protein 151 (pHZ-67)|zinc finger protein 60
Swissprots Q15932 F5H411 A0AV07 Q13105 B4DXB4 B7ZLQ9 Q9NUC9 Q5JYB2
Accessions AAA61327 EAW51757 EAW51758 Q13105 AK223618 BAD97338 AK226168 AK294796 BAG57917 AK299820 BAG61689 AK301896 BAG63326 AK302610 BAG63857 AK303823 BAG64771 AK309081 AK311083 AK315201 BAG37639 BC126163 AAI26164 BC143965 AAI43966 BC143968 BQ575263 BU634371 DB064089 U20647 AAC50256 Y09723 CAA70889 XM_005245986 XP_005246043 XM_005245987 XP_005246044 XM_011542085 XP_011540387 XM_011542086 XP_011540388 XM_011542087 XP_011540389 XM_011542088 XP_011540390 XM_011542089 XP_011540391 NM_001242884 NP_001229813 NM_001287603 NP_001274532 NM_001287604 NP_001274533 NM_003443 NP_003434
Function Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation. {ECO:0000269|PubMed:16142238, ECO:0000269|PubMed:19164764, ECO:0000269|PubMed:9308237, ECO:0000269|PubMed:9312026}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14739298, ECO:0000269|PubMed:9312026}.
Tissue Specificity Expressed in germinal center B-cells. {ECO:0000269|PubMed:16142238}.
Top Pathways Cell cycle, Transcriptional misregulation in cancer

Miz-1 Antibody - 9044 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing Myc/DDK-tagged full-length human Miz-1 (hMiz-1-Myc/DDK; +), using Miz-1 Antibody.

Miz-1 (B-10) - sc-136985 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Miz-1 (B-10) sc-136985. Western blot analysis of Miz-1 expression in SK-N-MC (A), SJRH30 (B), BC3H1 (C), L8 (D), Raji (E) and CCRF-CEM (F) whole cell lysate.

Miz-1 (N-17) - sc-5984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Miz-1 (N-17): sc-5984. Western blot analysis of Miz-1 expression in HCT 116 whole cell lysate.

Miz-1 (C-19) - sc-5987 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Miz-1 (C-19): sc-5987. Western blot analysis of Miz-1 expression in SK-N-MC (A), SJRH30 (B) and Raji (C) whole cell lysates.

Miz-1 (H-190) - sc-22837 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Miz-1 (G-18) - sc-5986 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Miz1 antibody - ab121232 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121232, at 1/250 dilution, staining Miz1 in Human bronchus tissue by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue. Note: shows strong nuclear and moderate cytoplasmic and membranous positivity in respiratory epithelial cells.

Anti-Miz1 antibody - N-terminal - ab139119 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Miz1 antibody - N-terminal (ab139119) at 1/100 dilution + NCI-H460 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142, AP) - LS-C273857 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142, APC) - LS-C273858 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142, Biotin) - LS-C273859 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142, FITC) - LS-C273860 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142, Azide-free, HRP) - LS-C273862 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142, PE) - LS-C273861 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142) - LS-C326436 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ZBTB17 / MIZ-1 Antibody (aa113-142) - LS-C157387 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ZBTB17 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The ZBTB17 antibody detected the ZBTB17 protein (arrow).

Miz-1/ZBTB17 Antibody - AF3760 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of Raji human Burkitt's lymphoma cell line and CEM human T-lymphoblastoid cell line. PVDF membrane was probed with 1 µg/mL of Human Miz‑1/ZBTB17 Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF3760) followed by HRP‑conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for Miz-1/ZBTB17 at approximately 100 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 1.

Miz-1/ZBTB17 Antibody - NBP1-81048 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Miz-1/ZBTB17 Antibody [NBP1-81048] - Immunohistochemical staining of human bronchus shows strong nuclear and moderate cytoplasmic and membranous positivity in respiratory epithelial cells.

Anti-ZBTB17 antibody produced in rabbit - HPA005789 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZBTB17: <B>Cat. No. HPA005789</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human nasopharyngeal tissue showing nuclear and cytoplasmic/membranous staining of respiratory epithelial cells.

ANTI-ZBTB17(N-TERMINAL) antibody produced in rabbit - SAB1305232 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZBTB17 (N-term): <B>Cat. No. SAB1305232</B>: ZBTB17 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35 μg/lane).

ZBTB17-Antibody-N-term - AP18958a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
ZBTB17 Antibody (N-term) (Cat. #AP18958a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ZBTB17 antibody detected the ZBTB17 protein (arrow).

ZBTB17 Antibody - N-terminal region (OAAB14496) - OAAB14496 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Human Miz-1/ZBTB17 Antibody - AF3760 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Detection of Human Miz‑1/ZBTB17 by Western Blot. Western blot shows lysates of Raji human Burkitt's lymphoma cell line and CEM human T-lymphoblastoid cell line. PVDF membrane was probed with 1 µg/mL of Human Miz-1/ZBTB17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3760) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017 ). A specific band was detected for Miz-1/ZBTB17 at approximately 100 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 1 .

Human Miz-1/ZBTB17 Affinity Purified Polyclonal Ab, Goat IgG - AF3760-SP from R&D Systems

Host Goat
Clonality Polyclonal
Detection of Human Miz‑1/ZBTB17 by Western Blot. Western blot shows lysates of Raji human Burkitt's lymphoma cell line and CEM human T-lymphoblastoid cell line. PVDF membrane was probed with 1 µg/mL of Human Miz‑1/ZBTB17 Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF3760) followed by HRP‑conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for Miz-1/ZBTB17 at approximately 100 kDa (as indicated). This experiment was conducted using Immunoblot Buffer Group 1.

Rabbit Anti-Human ZBTB17 (N-term) - 102-14071 from RayBiotech

Host Rabbit
ZBTB17 Antibody (N-term) (Cat# 102-14071) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ZBTB17 antibody detected the ZBTB17 protein (arrow).
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