NUDT18

Gene Symbol	NUDT18
Entrez Gene	79873
Alt Symbol	MTH3
Species	Human
Gene Type	protein-coding
Description	nudix (nucleoside diphosphate linked moiety X)-type motif 18
Other Description	2-hydroxy-dADP phosphatase\|7,8-dihydro-8-oxoguanine phosphatase\|8-oxo-dGDP phosphatase NUDT18\|mutT homolog 3\|mutT human homolog 3\|nucleoside diphosphate-linked moiety X motif 18\|nudix motif 18
Swissprots	Q8IZ75 Q9H687 Q6ZVK8
Accessions	EAW63719 Q6ZVK8 AK026147 BAB15376 AK124446 BAC85853 BC016902 AAH16902 DA015404 HQ447874 ADQ32358 XM_011544650 XP_011542952 NM_024815 NP_079091
Function	Mediates the hydrolyzis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8- oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP. Exhibited no or minimal hydrolyzis activity against 8-oxo-dGTP, 8- oxo-GTP, dGTP, GTP, dGDP and GDP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools. {ECO:0000269\|PubMed:22556419}.

NUDT18 (G-14) - sc-98051 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

NUDT18 (G-14): sc-98051. Western blot analysis of NUDT18 expression in non-transfected 293: sc-110760 (A), human NUDT18 transfected 293: sc-113667 (B) and HeLa (C) whole cell lysates.

NUDT18 (K-16) - sc-98052 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

NUDT18 (K-16): sc-98052. Western blot analysis of NUDT18 expression in HeLa whole cell lysate.

NUDT18 (S-16) - sc-98053 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Rabbit
Clonality	Polyclonal

Anti-NUDT18 antibody - ab82997 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NUDT18 antibody (ab82997) at 1 µg/ml (in 5% skim milk / PBS buffer) + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-NUDT18 antibody - ab69044 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-NUDT18 antibody (ab69044) at 1/500 dilutionLane 1 : NUDT18 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-NUDT18 antibody [1A5] - ab123903 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1A5

All lanes : Anti-NUDT18 antibody [1A5] (ab123903) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY NUDT18 cDNALysates/proteins at 5 µg per lane.

Anti-NUDT18 antibody [6B7] - ab118992 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	6B7

All lanes : Anti-NUDT18 antibody [6B7] (ab118992) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY NUDT18 cDNALysates/proteins at 5 µg per lane.

Anti-NUDT18 Antibody (clone 1A5) - LS-C173465 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1A5

IHC of paraffin-embedded Human pancreas tissue using anti-NUDT18 mouse monoclonal antibody.

Anti-NUDT18 Antibody (clone 5F9) - LS-C173487 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	5F9

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-NUDT18 mouse monoclonal antibody.

Anti-NUDT18 Antibody (clone 5D7) - LS-C173474 from LifeSpan Bioscience

Prices	$350.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	5D7

IHC of paraffin-embedded Human prostate tissue using anti-NUDT18 mouse monoclonal antibody.

Anti-NUDT18 Antibody (N-Terminus) - LS-C81320 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-NUDT18 Antibody (aa252-301) - LS-C81321 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-NUDT18 Antibody (clone 6B7) - LS-C173486 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	6B7

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NUDT18 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NUDT18.

Anti-NUDT18 Antibody (clone 1A8) - LS-C337539 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1A8

Anti-NUDT18 Antibody (clone 1B4) - LS-C173464 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1B4

NUDT18 Antibody (5D7) - NBP2-01432 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	5D7

Western Blot: NUDT18 Antibody (5D7) [NBP2-01432] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NUDT18 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NUDT18.

NUDT18 Antibody - H00079873-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: NUDT18 Antibody [H00079873-B01P] - Analysis of NUDT18 expression in transfected 293T cell line by NUDT18 polyclonal antibody. Lane 1: NUDT18 transfected lysate(35.53 KDa). Lane 2: Non-transfected lysate.

Anti-NUDT18 antibody produced in rabbit - HPA028581 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-NUDT18: <B>Cat. No. HPA028581</B>: Immunohistochemical staining of human vagina shows distinct positivity in squamous epithelial cells.

Anti-NUDT18 (304-315) antibody produced in rabbit - SAB1101989 from Sigma-Aldrich

Prices	$298.50
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human NUDT18 was separated on SDS-PAGE, blotted with Anti-NUDT18 (304-315) (<B>Cat. No. SAB1101989</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500 + NUDT18 immunizing peptide (human, 304-315)

Anti-NUDT18 antibody produced in mouse - SAB1407985 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-NUDT18: <B>Cat. No. SAB1407985</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~35.5 kDa using NUDT18 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-NUDT18 (ab1) antibody produced in rabbit - SAB2101660 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-NUDT18 (ab1): <B>Cat. No.SAB2101660</B>: NUDT18 in 293T cell lysate with NUDT18 antibody at 1.0 μg/mL.

NUDT18 antibody - N-terminal region (ARP48921_P050) - ARP48921_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

NUDT18 antibody - C-terminal region (ARP48922_P050) - ARP48922_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

NUDT18 antibody - GTX120944 from GeneTex

Prices	$149.00
Sizes	100 μl
Host	Rabbit
Clonality	Polyclonal

NUDT18 antibody, C-term - GTX46166 from GeneTex

Prices	$319.00
Sizes	50 μg
Host	Rabbit
Clonality	Polyclonal

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