WASF2

Gene Symbol WASF2
Entrez Gene 10163
Alt Symbol IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2
Species Human
Gene Type protein-coding
Description WAS protein family, member 2
Other Description WASP family Verprolin-homologous protein 2|WASP family protein member 2|WASP family protein member 4|protein WAVE-2|putative Wiskott-Aldrich syndrome protein family member 4|suppressor of cyclic-AMP receptor (WASP-family)|verprolin homology domain-containing protein 2|wiskott-Aldrich syndrome protein family member 2
Swissprots Q9UDY7 B4DZN0 O60794 Q9Y6W5
Accessions CAC18518 EAX07753 Q9Y6W5 AA736923 AB026542 BAA81795 AJ431612 AK024540 AK025566 AK075231 BAC11488 AK303011 BAG64142 AK304750 BAG65507 AY007122 BC001524 BC001855 BC012329 BC032380 BC032724 AAH32724 BC040943 AAH40943 DC300388 DC376823 HY001891 NM_001201404 NP_001188333 NM_006990 NP_008921
Function Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. {ECO:0000269|PubMed:10381382, ECO:0000269|PubMed:16275905}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=At the interface between the lamellipodial actin meshwork and the membrane. {ECO:0000250}.
Tissue Specificity Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle. {ECO:0000269|PubMed:10381382}.
Top Pathways Adherens junction, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Choline metabolism in cancer

Human WASF2 full length protein - ab160851 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160851 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human WASF2 protein fragment - ab160852 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160852 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human WASF2 Protein - H00010163-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human WASF2 Protein - H00010163-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

WASF2-Antibody-Center-Blocking-Peptide - BP14540c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

WASF2 / WAVE2 - H00010163-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

WASF2 / WAVE2 - H00010163-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

WASF2 / WAVE2 - H00010163-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

WASF2 / WAVE2 - H00010163-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Recombinant Human WASF2 protein, MYC/DDK-tagged - WASF2-1183H from Creative Biomart

Category Protein
Source HEK293 cells
Species Human

Recombinant Human WASF2 protein, GST-tagged - WASF2-1839H from Creative Biomart

Category Protein
Source Wheat Germ
Species Human

Recombinant Human WASF2 protein, GST-tagged - WASF2-1832H from Creative Biomart

Category Protein
Source Wheat Germ
Species Human

Recombinant Wiskott Aldrich Syndrome Protein Family, Member 2 (WASF2) - RPE773Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Wiskott Aldrich Syndrome Protein Family, Member 2 (WASF2) - RPE773Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Wiskott Aldrich Syndrome Protein Family, Member 2 (WASF2) - RPE773Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Human Wiskott-Aldrich syndrome protein family member 2(WASF2) - CSB-YP896553HU CSB-EP896553HU CSB-BP896553HU CSB-MP896553HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

WAVE2 (Central region) - WX1795 from ECM Biosciences

Category Peptide
Prices $55.00
Sizes 50 μg
Western blot of rat PC12 lysate. The blots were probed with anti-WAVE2 (Central region) in the presence (lane 2) or absence (lane 1) of WAVE2 (Central region) blocking peptide.

WASF2 / WAVE2 - TP308034 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
WASF2 / WAVE2

Wiskott-Aldrich syndrome protein family member 2 (WASF2) , Recombinant Protein - MBS1285525 from MyBioSource

Category Protein
Prices $2,110.00, $2,110.00, $2,570.00, $2,570.00
Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

WAVE2 (Central region) Peptide, Peptide - MBS474071 from MyBioSource

Category Peptide
Prices $130.00
Sizes 50 µg

WASF2 Protein - NBP2-37912PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

WASF2 Peptide, Human - M34GP17378H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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