WASF2

Gene Symbol WASF2
Entrez Gene 10163
Alt Symbol IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2
Species Human
Gene Type protein-coding
Description WAS protein family, member 2
Other Description WASP family Verprolin-homologous protein 2|WASP family protein member 2|WASP family protein member 4|protein WAVE-2|putative Wiskott-Aldrich syndrome protein family member 4|suppressor of cyclic-AMP receptor (WASP-family)|verprolin homology domain-containing protein 2|wiskott-Aldrich syndrome protein family member 2
Swissprots Q9UDY7 B4DZN0 O60794 Q9Y6W5
Accessions CAC18518 EAX07753 Q9Y6W5 AA736923 AB026542 BAA81795 AJ431612 AK024540 AK025566 AK075231 BAC11488 AK303011 BAG64142 AK304750 BAG65507 AY007122 BC001524 BC001855 BC012329 BC032380 BC032724 AAH32724 BC040943 AAH40943 DC300388 DC376823 HY001891 NM_001201404 NP_001188333 NM_006990 NP_008921
Function Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. {ECO:0000269|PubMed:10381382, ECO:0000269|PubMed:16275905}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Note=At the interface between the lamellipodial actin meshwork and the membrane. {ECO:0000250}.
Tissue Specificity Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle. {ECO:0000269|PubMed:10381382}.
Top Pathways Adherens junction, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Choline metabolism in cancer

WAVE2 CRISPR/Cas9 KO Plasmid (h) - sc-401675 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 HDR Plasmid (h) - sc-401675-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 Double Nickase Plasmid (h) - sc-401675-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 Double Nickase Plasmid (h2) - sc-401675-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 CRISPR Activation Plasmid (h) - sc-401675-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 CRISPR Activation Plasmid (h2) - sc-401675-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 Lentiviral Activation Particles (h) - sc-401675-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 Lentiviral Activation Particles (h2) - sc-401675-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WAVE2 siRNA (h) - sc-36833 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WAVE2 shRNA Plasmid (h) - sc-36833-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WAVE2 shRNA (h) Lentiviral Particles - sc-36833-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU107621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22777 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22777 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11759 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11759

WASF2 siRNA (Human) - CRH6862 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

WASF2 RNAi - H00010163-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

WASF2 - MBS8221416 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

WASF2 shRNA Plasmid (Human) - CHH6862 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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