GNL3L

Gene Symbol	GNL3L
Entrez Gene	54552
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	guanine nucleotide binding protein-like 3 (nucleolar)-like
Other Description	guanine nucleotide-binding protein-like 3-like protein|novel GTPase
Swissprots	Q9NVN8
Accessions	CAE89448 CBX47629 EAW93182 EAW93183 EAW93184 EAW93185 Q9NVN8 AK001475 BAA91712 AK022325 AK128277 BC003603 AAH03603 BC011720 AAH11720 BC022829 BQ674906 XM_011530799 XP_011529101 NM_001184819 NP_001171748 NM_019067 NP_061940
Function	Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. {ECO:0000269|PubMed:16251348, ECO:0000269|PubMed:17034816, ECO:0000269|PubMed:19487455, ECO:0000269|PubMed:21132010}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:17034816}.
Top Pathways	Ribosome biogenesis in eukaryotes

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GNL3L full length protein - ab162779 from Abcam Category Protein Source Wheat germ Species Human

GNL3L Antibody Blocking Peptide - LS-E695 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNL3L Antibody Blocking Peptide - LS-E21515 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNL3L Antibody Blocking Peptide - LS-E21516 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human GNL3L Protein - H00054552-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GNL3L-Antibody-N-term-Blocking-peptide - BP11045a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human GNL3L protein - orb246631 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

GNL3L Blocking Peptide - 33R-6234 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GNL3L Blocking Peptide - 33R-7687 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GNL3L - H00054552-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GNL3L - H00054552-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GNL3L fusion protein - ag9122 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GNL3L fusion protein - Ag9257 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human GNL3L, GST-tagged - GNL3L-13371H from Creative Biomart Category Protein Source E.coli Species Human

GNL3L Blocking Peptide - CBP3968 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Bovine

Recombinant Human Guanine nucleotide-binding protein-like 3-like protein(GNL3L) - CSB-YP865150HU CSB-BP865150HU CSB-MP865150HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Guanine nucleotide-binding protein-like 3-like protein - CSB-EP865150HU from Cusabio Category Protein Source E.coli Species Human

GNL3L Recombinant Protein Antigen - NBP2-32660PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GNL3L Blocking Peptide - abx162461 from Abbexa Category Peptide Species Human, Mouse, Bovine

GNL3L Recombinant Protein Antigen - NBP1-84618PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GNL3L Peptide, Human - M34GP06416H from Creative Peptides Category Peptide Source Synthetic. Species Human

GNL3L Recombinant Protein (OPCA02472) - OPCA02472 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Guanine nucleotide-binding protein-like 3-like protein - AP71532 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Guanine nucleotide-binding protein-like 3-like, Recombinant Protein - MBS9421394 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Guanine nucleotide-binding protein-like 3-like protein, Recombinant Protein - MBS1303021 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00, $1,380.00, $1,600.00, $1,600.00, $2,300.00, $2,745.00, $2,745.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

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