LEPROT

Gene Symbol LEPROT
Entrez Gene 54741
Alt Symbol LEPR, OB-RGRP, OBRGRP, VPS55
Species Human
Gene Type protein-coding
Description leptin receptor overlapping transcript
Other Description DnaJ (Hsp40) homolog, subfamily C, member 6|OB-R gene-related protein|endospanin-1|leptin receptor gene related protein|leptin receptor gene-related protein|leptin receptor overlapping transcript protein
Swissprots Q6FHL5 O15243
Accessions CAF86819 CAH25980 CAH59519 CBX85065 EAX06527 EAX06531 O15243 AK023598 AK026175 AK074841 BAG52014 AK094801 AK130096 AK309370 BC011027 AAH11027 BC036581 BC056250 AAH56250 BC140007 BI715133 BU677319 BX360952 CA434795 CB140261 CR541647 CAG46448 CR541737 CAG46537 EU832353 ACE87610 EU832438 ACE86923 Y12670 CAA73211 NM_001198681 NP_001185610 NM_001198683 NP_001185612 NM_017526 NP_059996
Function Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. {ECO:0000269|PubMed:18042720, ECO:0000269|PubMed:19907080}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}.
Tissue Specificity Expressed at the highest levels in heart and placenta and at a lesser extent in lung, liver, skeletal muscle, kidney and pancreas.

LEPROT CRISPR/Cas9 KO Plasmid (h) - sc-406321 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT HDR Plasmid (h) - sc-406321-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT Double Nickase Plasmid (h) - sc-406321-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT Double Nickase Plasmid (h2) - sc-406321-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT CRISPR Activation Plasmid (h) - sc-406321-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT CRISPR Activation Plasmid (h2) - sc-406321-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT Lentiviral Activation Particles (h) - sc-406321-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT Lentiviral Activation Particles (h2) - sc-406321-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT siRNA (h) - sc-88262 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LEPROT shRNA Plasmid (h) - sc-88262-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LEPROT shRNA (h) Lentiviral Particles - sc-88262-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Leptin R RNAi - H00003953-R06 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN11653 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11653 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LEPROT siRNA (Human) - CRJ0192 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LEPROT CRISPR/Cas9 KO Plasmid (h2) - sc-406321-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LEPROT HDR Plasmid (h2) - sc-406321-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human LEPROT (NM_001198681.1) - SHH329675 from Creative biogene

Category siRNA
Species Reactivities Human

Human LEPROT siRNA - orb270693 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LEPROT shRNA Plasmid (Human) - CHJ0192 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LEPROT miRNA 3'UTR clone - MiUTR4H-TG05029 from Creative biogene

Species Reactivities Human
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