Gene Symbol | UNG |
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Entrez Gene | 7374 |
Alt Symbol | DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2 |
Species | Human |
Gene Type | protein-coding |
Description | uracil-DNA glycosylase |
Other Description | UDG|uracil-DNA glycosylase 1, uracil-DNA glycosylase 2 |
Swissprots | Q93028 B2R8Y1 O00637 O00719 A8K5M6 P13051 |
Accessions | AAM77695 ADP92134 ADP92135 ADP92136 ADP92137 ADP92138 ADP92139 ADP92140 ADP92141 ADP92142 ADP92143 ADP92144 ADP92145 ADP92146 ADP92147 ADP92148 ADP92149 ADP92150 ADP92151 ADP92152 ADP92153 ADP92154 ADP92155 ADP92156 ADP92157 ADP92158 ADP92159 ADP92160 ADP92161 ADP92162 ADP92163 ADP92164 ADP92165 ADP92166 ADP92167 ADP92168 ADP92169 ADP92170 ADP92171 ADP92172 ADP92173 ADP92174 ADP92175 ADP92176 ADP92177 ADP92178 ADP92179 ADP92180 ADP92181 ADP92182 ADP92183 ADP92184 ADP92185 ADP92186 ADP92187 ADP92188 ADP92189 ADP92190 ADP92191 ADP92192 ADP92193 ADP92194 ADP92195 ADP92196 ADP92197 ADP92198 ADP92199 ADP92200 ADP92201 ADP92202 ADP92203 ADP92204 ADP92205 ADP92206 ADP92207 ADP92208 ADP92209 ADP92210 ADP92211 ADP92212 ADP92213 CAA03797 CAA61578 CAA61579 CBX87166 EAW97846 EAW97847 EAW97848 EAW97849 EAW97850 P13051 AK291341 BAF84030 AK299416 BAG61398 AK313552 BAG36328 BC015205 AAH15205 BC050634 AAH50634 BG326541 BM928006 BQ950839 BU622689 CR541673 CAG46474 CR749342 CAH18195 DB045515 GQ129388 ACT64522 GQ129389 ACT64523 X15653 CAA33679 Y09008 CAA70211 NM_003362 NP_003353 NM_080911 NP_550433 |
Function | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
Subcellular Location | Isoform 1: Mitochondrion. |
Tissue Specificity | Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. |
Top Pathways | Primary immunodeficiency, Base excision repair |
UDG (B-7) - sc-390255 from Santa Cruz Biotechnology
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UDG (FL-313) - sc-28719 from Santa Cruz Biotechnology
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UDG (K-20) - sc-14570 from Santa Cruz Biotechnology
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UDG (P-14) - sc-14569 from Santa Cruz Biotechnology
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UDG (k1C12) - sc-73639 from Santa Cruz Biotechnology
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Anti-UNG antibody - ab23926 from Abcam
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Anti-UNG antibody - ab47680 from Abcam
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Anti-UNG antibody - ab89640 from Abcam
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Anti-UNG antibody - ab101283 from Abcam
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Anti-UNG antibody - ab13668 from Abcam
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Anti-UNG antibody [2F3] - ab118977 from Abcam
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Anti-UNG antibody [EPR4371] - ab109214 from Abcam
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Anti-UNG antibody [k1C12] - ab58976 from Abcam
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Anti-UNG antibody - Carboxyterminal end - ab62520 from Abcam
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Anti-UNG / Uracil DNA Glycosylase Antibody (N-Terminus) IHC-plus⢠- LS-B1434 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (aa172-221) - LS-C200805 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (clone 1A11) - LS-C173288 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (clone 1F8) - LS-C173339 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (clone 1G2) - LS-C173410 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (C-Terminus) IHC-plus⢠- LS-B615 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (clone 2B5) - LS-C337514 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (clone 1F8) - LS-C337489 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (N-Terminus) IHC-plus⢠- LS-B10107 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (aa1-313, clone K1C12) IHC-plus⢠- LS-B2938 from LifeSpan Bioscience
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Anti-UNG / Uracil DNA Glycosylase Antibody (clone 2C12) - LS-C337501 from LifeSpan Bioscience
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