| Gene Symbol |
LAX1
|
| Entrez Gene |
54900
|
| Alt Symbol |
LAX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lymphocyte transmembrane adaptor 1
|
| Other Description |
LAT-like membrane associated protein|linker for activation of x cells|lymphocyte transmembrane adapter 1|membrane-associated adapter protein LAX
|
| Swissprots |
Q6NSZ6 Q9NXB4 Q8IWV1 J3KP69 B7Z744
|
| Accessions |
EAW91489 EAW91490 EAW91491 Q8IWV1 AK000347 BAA91101 AK225331 AK301076 BAG62682 AK301421 BAH13480 AY090784 AAM09818 BC069650 AAH69650 BC089408 AAH89408 DC414389 XM_006711397 XP_006711460 NM_001136190 NP_001129662 NM_001282878 NP_001269807 NM_017773 NP_060243
|
| Function |
Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. {ECO:0000269|PubMed:12359715}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:12359715}; Single-pass type III membrane protein {ECO:0000269|PubMed:12359715}.
|
| Tissue Specificity |
Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines. {ECO:0000269|PubMed:12359715}.
|
![Western Blot: LAX1 Overexpression Lysate (Adult Normal) [NBP2-06919] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LAX1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8344_LAX1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06919-img0001.jpg)