Gene Symbol | CACNG5 |
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Entrez Gene | 27091 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | calcium channel, voltage-dependent, gamma subunit 5 |
Other Description | TARP gamma-5|neuronal voltage-gated calcium channel gamma-5 subunit|transmembrane AMPAR regulatory protein gamma-5|voltage-dependent calcium channel gamma-5 subunit |
Swissprots | Q9UF02 Q9UHM3 Q8WXS7 Q547R3 A8K2A6 |
Accessions | AAF03089 CAC36508 EAW89018 EAW89019 Q9UF02 AF148220 AAF00132 AF361351 AAL50046 AF458898 AAM00595 AK290171 BAF82860 BC101607 AAI01608 BC101633 AAI01634 XM_011524613 XP_011522915 NM_145811 NP_665810 NM_014404 |
Function | Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. |
Top Pathways | MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
L-type Ca ++ CP γ5 (L-14) - sc-107680 from Santa Cruz Biotechnology
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Anti-Calcium channel L type DHPR gamma 5 subunit antibody - ab81002 from Abcam
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Anti-Calcium channel L type DHPR gamma 5 subunit antibody - ab104591 from Abcam
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Anti-Calcium channel L type DHPR gamma 5 subunit antibody - ab96713 from Abcam
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Anti-Calcium channel L type DHPR gamma 5 subunit antibody - ab28278 from Abcam
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Anti-Calcium channel L type DHPR gamma 5 subunit antibody - C-terminal - ab135586 from Abcam
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Anti-CACNG5 Antibody (aa150-200) - LS-C94070 from LifeSpan Bioscience
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Anti-CACNG5 Antibody (aa192-220) - LS-C99364 from LifeSpan Bioscience
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Anti-CACNG5 Antibody IHC-plus⢠- LS-B4222 from LifeSpan Bioscience
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CACNG5 Antibody - NBP1-20121 from Novus Biologicals
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CACNG5 Antibody - NBP1-70369 from Novus Biologicals
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CACNG5 Antibody - NBP2-14432 from Novus Biologicals
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Anti-CACNG5 antibody produced in rabbit - HPA050115 from Sigma-Aldrich
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ANTI-CACNG5 (C-TERM) antibody produced in rabbit - SAB1303051 from Sigma-Aldrich
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Anti-CACNG5 antibody produced in rabbit - SAB2700270 from Sigma-Aldrich
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Anti-Calcium Channel (γ5 subunit) antibody produced in rabbit - C6488 from Sigma-Aldrich
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CACNG5-Antibody-C-term - AP6630b from Abgent, a WuXi AppTec company
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CACNG5 Antibody - C-terminal region (OAAB03661) - OAAB03661 from Aviva Systems Biology
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Cav gamma 5 antibody - GTX103664 from GeneTex
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Anti -CACNG5 (Voltage-dependent Calcium Channel gamma-5 Subunit, Neuronal Voltage-gatedCalcium Channel gamma-5 Subunit) - C0104-95B from USBiological Life Science
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CACNG5 antibody - orb73746 from Biorbyt
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CACNG5 antibody - 70R-12740 from Fitzgerald
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CACNG5 antibody - 70R-16120 from Fitzgerald
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CACNG5 antibody (OAGA00248) - OAGA00248 from Aviva Systems Biology
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CACNG5 Antibody - abx032904 from Abbexa
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