Gene Symbol | PEMT |
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Entrez Gene | 10400 |
Alt Symbol | PEAMT, PEMPT, PEMT2, PNMT |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylethanolamine N-methyltransferase |
Other Description | - |
Swissprots | Q9UBM1 B4DY41 D3DXC3 Q6IAQ5 Q86VL3 Q9BW86 Q9Y6V9 A8MZ66 Q9UHY6 |
Accessions | AAK19172 ACB21050 EAW55700 EAW55701 EAW55702 Q9UBM1 AB029821 BAA82407 AF044214 AAQ13425 AF113126 AAF14867 AF176806 AAD53291 AF176807 AAD53292 AK302251 BAG63603 BC000557 AAH00557 BC050593 AAH50593 BM011377 CR457099 CAG33380 HQ448599 ADQ33077 XM_006721418 XP_006721481 NM_001267551 NP_001254480 NM_001267552 NP_001254481 NM_007169 NP_009100 NM_148172 NP_680477 NM_148173 NP_680478 |
Function | Catalyzes three sequential methylation reactions of phosphatidylethanolamine (PE) by AdoMet, thereby producing phosphatidylcholine (PC). |
Subcellular Location | Isoform 1: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20860552}; Multi-pass membrane protein {ECO:0000305}. Mitochondrion membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Found in endoplasmic reticulum where most PEMT activity is generated and in mitochondria. {ECO:0000250}. |
Top Pathways | Glycerophospholipid metabolism |
PEMT 293T Cell Transient Overexpression Lysate(Denatured) - H00010400-T01 from Acris Antibodies
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PEMT 293T Cell Transient Overexpression Lysate(Denatured) - H00010400-T02 from Acris Antibodies
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PEMT overexpression lysate - LY402097 from Acris Antibodies
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PEMT overexpression lysate - LY407769 from Acris Antibodies
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PEMT overexpression lysate - LY407770 from Acris Antibodies
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PEMT 293 Cell Lysate - 404363 from ABBIOTEC
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PEMT 293 Cell Lysate - 404364 from ABBIOTEC
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PEMT 293 Cell Lysate - 401856 from ABBIOTEC
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PEMT Overexpression Lysate (Denatured) - H00010400-T02 from Novus Biologicals
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PEMT Overexpression Lysate (Denatured) - H00010400-T01 from Novus Biologicals
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PEMT Overexpression Lysate (Native) - NBL1-14286 from Novus Biologicals
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PEMT Overexpression Lysate (Native) - NBL1-14288 from Novus Biologicals
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PEMT Overexpression Lysate (Native) - NBL1-14287 from Novus Biologicals
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PEMT (h): 293T Lysate - sc-116384 from Santa Cruz Biotechnology
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PEMT Over-expression Lysate Product - GWB-C4389F from Genway Biotech
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PEMT Over-expression Lysate Product - GWB-C18ABE from Genway Biotech
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PEMT Over-expression Lysate Product - GWB-A3CA14 from Genway Biotech
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Panoply™ Human PEMT Knockdown Stable Cell Line - CSC-DC011588 from Creative biogene
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