PEMT

Gene Symbol	PEMT
Entrez Gene	10400
Alt Symbol	PEAMT, PEMPT, PEMT2, PNMT
Species	Human
Gene Type	protein-coding
Description	phosphatidylethanolamine N-methyltransferase
Other Description	-
Swissprots	Q9UBM1 B4DY41 D3DXC3 Q6IAQ5 Q86VL3 Q9BW86 Q9Y6V9 A8MZ66 Q9UHY6
Accessions	AAK19172 ACB21050 EAW55700 EAW55701 EAW55702 Q9UBM1 AB029821 BAA82407 AF044214 AAQ13425 AF113126 AAF14867 AF176806 AAD53291 AF176807 AAD53292 AK302251 BAG63603 BC000557 AAH00557 BC050593 AAH50593 BM011377 CR457099 CAG33380 HQ448599 ADQ33077 XM_006721418 XP_006721481 NM_001267551 NP_001254480 NM_001267552 NP_001254481 NM_007169 NP_009100 NM_148172 NP_680477 NM_148173 NP_680478
Function	Catalyzes three sequential methylation reactions of phosphatidylethanolamine (PE) by AdoMet, thereby producing phosphatidylcholine (PC).
Subcellular Location	Isoform 1: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20860552}; Multi-pass membrane protein {ECO:0000305}. Mitochondrion membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Found in endoplasmic reticulum where most PEMT activity is generated and in mitochondria. {ECO:0000250}.
Top Pathways	Glycerophospholipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PEMT CRISPR/Cas9 KO Plasmid (h) - sc-409484 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT HDR Plasmid (h) - sc-409484-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT Double Nickase Plasmid (h) - sc-409484-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT Double Nickase Plasmid (h2) - sc-409484-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT CRISPR Activation Plasmid (h) - sc-409484-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT CRISPR Activation Plasmid (h2) - sc-409484-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT Lentiviral Activation Particles (h) - sc-409484-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT Lentiviral Activation Particles (h2) - sc-409484-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PEMT siRNA (h) - sc-106913 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PEMT shRNA Plasmid (h) - sc-106913-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PEMT shRNA (h) Lentiviral Particles - sc-106913-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU122571 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16619 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16619 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01343 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr01343

PEMT siRNA (Human) - CRH7049 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PEMT RNAi - H00010400-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PEMT RNAi - H00010400-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human PEMT (NM_007169.2) - SHH373492 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PEMT(NM_007169.2) - SHR095428 from Creative biogene Category siRNA Species Reactivities Human

PEMT shRNA Plasmid (Human) - CHH7049 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PEMT miRNA 3'UTR clone - MiUTR1H-07782 from Creative biogene Species Reactivities Human

PEMT miRNA 3'UTR clone - MiUTR3H-04940 from Creative biogene Species Reactivities Human

PEMT miRNA 3'UTR clone - MiUTR3H-04941 from Creative biogene Species Reactivities Human

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