| Gene Symbol |
PIRT
|
| Entrez Gene |
644139
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphoinositide-interacting regulator of transient receptor potential channels
|
| Other Description |
phosphoinositide-interacting protein|phosphoinositide-interacting regulator of TRPV1
|
| Swissprots |
P0C851 B7Z648
|
| Accessions |
EAW89989 P0C851 AK021549 AK299808 BAH13134 AK300493 BAG62207 DC332889 NM_001101387 NP_001094857
|
| Function |
Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5- bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|