Gene Symbol | VAT1 |
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Entrez Gene | 10493 |
Alt Symbol | VATI |
Species | Human |
Gene Type | protein-coding |
Description | vesicle amine transport 1 |
Other Description | membrane protein of cholinergic synaptic vesicles|synaptic vesicle membrane protein VAT-1 homolog|vesicle amine transport protein 1 homolog (T. californica) |
Swissprots | Q96A39 Q13035 Q99536 B0AZP7 Q9BUT8 A8K345 Q5BKZ7 B4DPX4 |
Accessions | AAC37596 EAW60917 EAW60918 Q99536 AK097072 BAG53420 AK290460 BAF83149 AK298536 BAG60736 AK315838 BAF98729 BC001913 AAH01913 BC008725 AAH08725 BC014279 AAH14279 BC015041 AAH15041 BC068489 BC090858 AAH90858 BT007369 AAP36033 HQ258013 ADR82767 U18009 AAA95990 U25779 AAA93230 NM_006373 NP_006364 |
Function | Possesses ATPase activity (By similarity). Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2). {ECO:0000250, ECO:0000269|PubMed:12898150, ECO:0000269|PubMed:17105775, ECO:0000269|PubMed:19508442}. |
Subcellular Location | Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein. Note=The majority is localized in the cytoplasm and a small amount is associated with mitochondria. {ECO:0000250}. |
Tissue Specificity | Expressed in brain. Also expressed in glioblastoma cells. {ECO:0000269|PubMed:19508442}. |
VAT1 (G-12) - sc-107348 from Santa Cruz Biotechnology
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VAT1 (P-13) - sc-107349 from Santa Cruz Biotechnology
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Anti-VAT1 antibody - ab89138 from Abcam
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Anti-VAT1 antibody - N-terminal - ab104318 from Abcam
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Anti-VAT1 Antibody (N-Terminus) - LS-C345751 from LifeSpan Bioscience
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Anti-VAT1 Antibody (aa71-120) - LS-C116455 from LifeSpan Bioscience
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VAT1 Antibody - NBP1-57008 from Novus Biologicals
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VAT1 Antibody - H00010493-A01 from Novus Biologicals
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VAT Polyclonal Antibody - bs-1833R from Bioss
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Anti-VAT1 (236-250) antibody produced in rabbit - SAB1100727 from Sigma-Aldrich
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Anti-VAT1 (121-133) antibody produced in rabbit - SAB1100726 from Sigma-Aldrich
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Monoclonal Anti-VAT1, (C-terminal) antibody produced in mouse - SAB1402519 from Sigma-Aldrich
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Anti-VAT1 antibody produced in rabbit - HPA045170 from Sigma-Aldrich
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VAT1 antibody - N-terminal region (ARP52167_P050) - ARP52167_P050 from Aviva Systems Biology
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VAT1 Antibody - N-terminal region (ARP74336_P050) - ARP74336_P050 from Aviva Systems Biology
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VAT1 (N-term) antibody - AP46098PU-N from Acris Antibodies
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VAT1 antibody - H00010493-A01 from Acris Antibodies
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VAT1 antibody - H00010493-M07 from Acris Antibodies
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Mouse Anti-Human VAT1 - 101-11920 from RayBiotech
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VAT1 antibody - 22016-1-AP from Proteintech Group
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VAT1, Monoclonal Antibody - MBS6007285 from MyBioSource
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VAT1 Antibody - GWB-MS495I from Genway Biotech
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Anti-VAT1 (aa 294-392) polyclonal antibody - DPAB-DC223 from Creative Diagnostics
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Vesicle Amine Transport protein-1, Polyclonal Antibody - MBS588294 from MyBioSource
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Vesicle Amine Transport protein-1, Polyclonal Antibody - MBS588230 from MyBioSource
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