CENPT

Gene Symbol	CENPT
Entrez Gene	80152
Alt Symbol	C16orf56, CENP-T
Species	Human
Gene Type	protein-coding
Description	centromere protein T
Other Description	interphase centromere complex protein 22
Swissprots	Q96NK9 Q96I29 Q96IC6 Q9H901 Q96BT3
Accessions	EAW83178 EAW83179 Q96BT3 AK023173 BAB14445 AK055237 BAB70884 AK056097 BAG51624 AK125366 AK225399 AK291527 BAF84216 AK297570 BAG59961 AK300887 BAG62529 AK301621 BAG63106 BC007642 AAH07642 BC007864 AAH07864 BC015202 AAH15202 BC042204 BX648617 CD242240 XM_006721277 XP_006721340 XM_011523344 XP_011521646 XM_011523345 XP_011521647 NM_025082 NP_079358
Function	Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome- associated complex that binds specifically to histone H3- containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis. {ECO:0000269|PubMed:16716197, ECO:0000269|PubMed:21529714, ECO:0000269|PubMed:21695110}.
Subcellular Location	Nucleus. Chromosome, centromere, kinetochore. Note=Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CENPT full length protein - ab164207 from Abcam Category Protein Source Wheat germ Species Human

CENPT Antibody Blocking Peptide - LS-E24924 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CENPT Protein - H00080152-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

CENP-T - H00080152-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Recombinant Human Centromere protein T(CENPT) - CSB-YP005221HU CSB-EP005221HU CSB-BP005221HU CSB-MP005221HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CENP-T - TP303693 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Centromere protein T (CENPT), Recombinant Protein - MBS1317539 from MyBioSource Category Protein Prices $1,355.00, $1,355.00, $1,575.00, $1,575.00, $2,255.00, $2,255.00, $2,720.00, $2,720.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CENPT Recombinant Protein Antigen - NBP2-34093PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CENPT-Antibody-C-term-Blocking-Peptide - BP9843b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CENPT Peptide, Human - M34GP02978H from Creative Peptides Category Peptide Source Synthetic. Species Human

CENPT Recombinant Protein Antigen - NBP2-58946PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Search more