Gene Symbol | TFAP2E |
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Entrez Gene | 339488 |
Alt Symbol | AP2E |
Species | Human |
Gene Type | protein-coding |
Description | transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) |
Other Description | AP2-epsilon|activating enhancer-binding protein 2-epsilon|adaptor-related protein complex 2, epsilon subunit|transcription factor AP-2-epsilon |
Swissprots | Q6VUC0 Q8IW12 |
Accessions | EAX07409 Q6VUC0 AY326454 AAQ91614 BC041175 AAH41175 BC150147 NM_178548 NP_848643 |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250|UniProtKB:Q6VUP9}. |
Tissue Specificity | Expressed in skin, primary keratinocytes, immortalized keratinocytes, and HeLa cell line. {ECO:0000269|PubMed:14636996}. |
AP-2ε (E-12) - sc-131391 from Santa Cruz Biotechnology
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AP-2ε (N-12) - sc-131393 from Santa Cruz Biotechnology
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AP-2ε (T-25) - sc-101887 from Santa Cruz Biotechnology
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Anti-TFAP2E antibody - ab89965 from Abcam
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Anti-TFAP2E antibody - ab169428 from Abcam
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Anti-TFAP2E antibody - ab56295 from Abcam
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Anti-TFAP2E Antibody (aa304-330) - LS-C204012 from LifeSpan Bioscience
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Anti-TFAP2E Antibody (C-Terminus) - LS-C31828 from LifeSpan Bioscience
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Anti-TFAP2E Antibody (N-Terminus) - LS-C109627 from LifeSpan Bioscience
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AP-2 epsilon/TFAP2E Antibody [Unconjugated] - AF5060 from Novus Biologicals
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AP-2 epsilon/TFAP2E Antibody - H00339488-B01 from Novus Biologicals
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Anti-TFAP2E, (N-terminal) antibody produced in rabbit - SAB2103724 from Sigma-Aldrich
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Anti-TFAP2E antibody produced in rabbit - AV40023 from Sigma-Aldrich
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TFAP2E antibody - N-terminal region (ARP31976_P050) - ARP31976_P050 from Aviva Systems Biology
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TFAP2E antibody - C-terminal region (ARP40023_T100) - ARP40023_T100 from Aviva Systems Biology
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Human AP-2 epsilon Antibody - AF5060 from R&D Systems
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Human AP-2 epsilon Affinity Purified Polyclonal Ab, Goat IgG - AF5060-SP from R&D Systems
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TFAP2E antibody - 25829-1-AP from Acris Antibodies
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TFAP2E antibody - H00339488-B01 from Acris Antibodies
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TFAP2E Antibody - 29-175 from ProSci
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TFAP2E antibody - 25829-1-AP from Proteintech Group
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TFAP2E Antibody - GWB-ML221E from Genway Biotech
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TFAP2E Antibody - GWB-B9912A from Genway Biotech
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Anti-TFAP2E monoclonal antibody - DCABH-17077 from Creative Diagnostics
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Anti-TFAP2E (full length) polyclonal antibody - DPABH-08053 from Creative Diagnostics
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