Gene Symbol | KRT71 |
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Entrez Gene | 112802 |
Alt Symbol | HYPT13, K6IRS1, KRT6IRS, KRT6IRS1 |
Species | Human |
Gene Type | protein-coding |
Description | keratin 71, type II |
Other Description | CK-71|K71|cytokeratin-71|hK6irs|hK6irs1|keratin 6 irs|keratin, type II cytoskeletal 71|keratin-71|type II inner root sheath-specific keratin-K6irs1|type-II keratin Kb34 |
Swissprots | Q96DU2 Q3SY84 B3KVC1 Q3SY85 |
Accessions | EAW96636 Q3SY84 AJ308599 CAC43429 AJ308600 AJ308601 AK122795 BAG53733 BC103917 AAI03918 BC103918 AAI03919 EU832765 ACE87776 GQ129308 ACT64442 NM_033448 NP_258259 |
Function | Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. {ECO:0000269|PubMed:22592156}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22592156}. |
Tissue Specificity | Highly expressed in hair follicles from scalp. Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in the all 3 IRS layers: the cuticle, the Henle and the Huxley layers. Also detected in the pseudopods of specialized Huxley cells, termed Fluegelzellen, along the area of differentiated Henle cells (at protein level). {ECO:0000269|PubMed:11982755, ECO:0000269|PubMed:12648212, ECO:0000269|PubMed:16874310, ECO:0000269|PubMed:22592156}. |
Human KRT71 full length protein - ab164982 from Abcam
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Human KRT71 protein fragment - ab164983 from Abcam
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KRT71 / Keratin 71 Antibody Blocking Peptide - LS-E23831 from LifeSpan Bioscience
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Recombinant Human Cytokeratin 71 Protein - H00112802-Q01 from Novus Biologicals
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Recombinant Human Cytokeratin 71 Protein - H00112802-P01 from Novus Biologicals
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Cytokeratin 71 - H00112802-P01-10 from Acris Antibodies
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Cytokeratin 71 - H00112802-P01-25 from Acris Antibodies
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Cytokeratin 71 - H00112802-Q01-10 from Acris Antibodies
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Cytokeratin 71 - H00112802-Q01-25 from Acris Antibodies
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KRT71 fusion protein - Ag23536 from Proteintech Group
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Recombinant Keratin 71 (KRT71) - RPM918Mu01 from Uscn Life Science Inc.
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Recombinant Human Keratin, type II cytoskeletal 71(KRT71) - CSB-YP660951HU CSB-EP660951HU CSB-BP660951HU CSB-MP660951HU from Cusabio
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KRT71 Peptide, Human - M34GP08393H from Creative Peptides
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Keratin, type II cytoskeletal 71 (KRT71), Recombinant Protein - MBS1433872 from MyBioSource
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