CHML

Gene Symbol CHML
Entrez Gene 1122
Alt Symbol REP2
Species Human
Gene Type protein-coding
Description choroideremia-like (Rab escort protein 2)
Other Description choroideraemia-like protein|choroideremia-like protein|rab proteins geranylgeranyltransferase component A 2
Swissprots B2RAB9 P26374 Q9H1Y4 Q17RE0
Accessions AAO15716 EAW70100 P26374 AK000933 AK023423 AK314125 BAG36816 BC117360 AAI17361 BG108374 BI088411 BM457359 BM470658 BM557064 BM763291 BM806625 BQ775652 BU187416 BU195066 CB160778 CN415289 DA612361 X64728 CAA45979 NM_001821 NP_001812
Function Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. {ECO:0000269|PubMed:12356470, ECO:0000269|PubMed:15186776, ECO:0000269|PubMed:8294464}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12356470}.

REP-2 (C-20) - sc-14768 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CHML antibody - ab92906 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHML antibody (ab92906) at 1/500 dilutionLane 1 : extracts from COLO cellsLane 2 : extracts from COLO cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-CHML antibody - ab167019 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHML antibody (ab167019) at 1/500 dilutionLane 1 : COLO cell extractLane 2 : COLO cell extract with synthesized peptide

Anti-CHML antibody - ab194456 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-CHML antibody (ab194456) at 1/500 dilution + HepG2 cell lysate at 50 µgdeveloped using the ECL technique

Anti-CHML antibody - C-terminal - ab191316 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CHML antibody - C-terminal (ab191316) at 1/1000 dilution + HT-1080 cell line lysate at 35 µgSecondaryGoat anti-rabbit IgG H&L(HRP) at 1/5000 dilution

Anti-CHML antibody - Carboxyterminal end - ab56143 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHML Antibody (aa624-656) - LS-C344229 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded M. cerebellum section using CHML Antibody. Antibody was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Anti-CHML Antibody (C-Terminus) - LS-C46955 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHML Antibody - LS-C306943 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CHML Antibody (aa170-215) - LS-C313913 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHML Antibody - LS-C309907 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHML Antibody (aa122-171) - LS-C29824 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-CHML Antibody (clone 5G4) - LS-C196909 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G4
Detection limit for recombinant GST tagged CHML is approximately 0.1 ng/ml as a capture antibody.

Anti-CHML Antibody (aa128-177) IHC-plus™ - LS-B8583 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CHML antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8583 dilution 5 ug/ml.

CHML Antibody - NBP1-87142 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CHML Antibody [NBP1-87142] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

CHML Antibody - H00001122-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CHML Antibody [H00001122-D01P] - Analysis of CHML expression in HeLa.

CHML Antibody (5G4) - H00001122-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G4
ELISA: CHML Antibody (5G4) [H00001122-M03] - Detection limit for recombinant GST tagged CHML is approximately 0.1ng/ml as a capture antibody.

CHML Antibody - H00001122-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CHML Antibody [H00001122-A01] - Western Blot analysis of CHML expression in HepG2 ( Cat # L019V1 ).

CHML Antibody - H00001122-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: CHML Antibody [H00001122-B01] - analysis of CHML expression in transfected 293T cell line by CHML MaxPab polyclonal antibody (B01). Lane 1: CHML transfected lysate (74.10 KDa). Lane 2: Non-transfected lysate.

CHML Antibody - H00001122-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CHML antibody produced in rabbit - SAB1410170 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHML: <B>Cat. No. SAB1410170</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~74.1 kDa using HeLa lysate.

Anti-CHML antibody produced in rabbit - SAB4500232 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CHML: <B>Cat. No. SAB4500232</B>: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Anti-CHML antibody. Cells on the left were treated with the Anti-CHML antibody. Cells on the right (negative control) were treated with both Anti-CHML antibody and the synthesized immunogen peptide.

Anti-CHML antibody produced in rabbit - HPA029628 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CHML: <B>Cat. No. HPA029628</B>: Immunohistochemical staining of human cerebellum shows moderate cytoplasmic and nuclear positivity in purkinje cells.

Anti-CHML antibody produced in mouse - SAB1405617 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHML: <B>Cat. No. SAB1405617</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~72.2 kDa using CHML transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-CHML antibody produced in mouse - WH0001122M3 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5G4
<B>Immunoblotting</B><BR/>Monoclonal Anti-CHML, <B>Cat. No. WH0001122M3</B> used at the antibody concentration: 1 μg/mL. Specific band of ~38.21 kDa using immunogen protein lysate.
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