MYO1C

Gene Symbol	MYO1C
Entrez Gene	4641
Alt Symbol	MMI-beta, MMIb, NMI, myr2
Species	Human
Gene Type	protein-coding
Description	myosin IC
Other Description	myosin I beta|myosin-I beta|myosin-Ic|nuclear myosin I|unconventional myosin-Ic
Swissprots	Q6NVJ7 Q86Y95 Q4LE56 O00159
Accessions	EAW90619 EAW90620 O00159 AB210015 BAE06097 AI220881 AK172742 AK292910 BAF85599 AK295761 BAH12181 AK304782 BAH14256 BC044891 AAH44891 BC068013 AAH68013 BC127784 AAI27785 BP255642 BP284965 CA422782 CD050346 CN313279 DB241937 X98507 CAA67131 NM_001080779 NP_001074248 NM_001080950 NP_001074419 NM_033375 NP_203693
Function	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes. {ECO:0000269|PubMed:24636949}.
Subcellular Location	Isoform 3: Nucleus, nucleoplasm. Nucleus, nucleolus. Nucleus, nuclear pore complex. Note=Colocalizes with RNA polymerase II in the nucleus. Colocalizes with RNA polymerase I in nucleoli (By similarity). In the nucleolus, is localized predominantly in dense fibrillar component (DFC) and in granular component (GC). Accumulates strongly in DFC and GC during activation of transcription. Colocalizes with transcription sites. Colocalizes in the granular cortex at the periphery of the nucleolus with RPS6. Colocalizes in nucleoplasm with RPS6 and actin that are in contact with RNP particles. Colocalizes with RPS6 at the nuclear pore level. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Myosin Ic (13) - sc-136544 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Myosin Ic (C-19) - sc-130177 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Myosin Ic (N-16) - sc-32702 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Myosin 1C antibody - ab51261 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Myosin 1C antibody - ab154498 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Myosin 1C antibody - ab94539 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Myosin 1C antibody [EPR14771] - ab194828 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR14771

Anti-Myosin 1C antibody - Carboxyterminal end - ab71486 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody - LS-C346146 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (C-Terminus, APC) - LS-C279858 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (C-Terminus, AP) - LS-C279856 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (N-Terminus) - LS-C144855 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (C-Terminus, Biotin) - LS-C279859 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (C-Terminus, Azide-free, HRP) - LS-C279861 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (C-Terminus, FITC) - LS-C279860 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody - LS-C295499 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (C-Terminus, PE) - LS-C279862 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (aa143-192) - LS-C110896 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (Biotin) - LS-C298685 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (aa728-987, Biotin) - LS-C298684 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (FITC) - LS-C305373 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (aa728-987, FITC) - LS-C305374 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody (C-Terminus) - LS-C327970 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MYO1C Antibody - LS-C164713 from LifeSpan Bioscience Prices $295.00 Sizes 100 µl Host Mouse Clonality Monoclonal

Anti-MYO1C Antibody (aa728-987) - LS-C295500 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

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