MYO1C

Gene Symbol MYO1C
Entrez Gene 4641
Alt Symbol MMI-beta, MMIb, NMI, myr2
Species Human
Gene Type protein-coding
Description myosin IC
Other Description myosin I beta|myosin-I beta|myosin-Ic|nuclear myosin I|unconventional myosin-Ic
Swissprots Q6NVJ7 Q86Y95 Q4LE56 O00159
Accessions EAW90619 EAW90620 O00159 AB210015 BAE06097 AI220881 AK172742 AK292910 BAF85599 AK295761 BAH12181 AK304782 BAH14256 BC044891 AAH44891 BC068013 AAH68013 BC127784 AAI27785 BP255642 BP284965 CA422782 CD050346 CN313279 DB241937 X98507 CAA67131 NM_001080779 NP_001074248 NM_001080950 NP_001074419 NM_033375 NP_203693
Function Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes. {ECO:0000269|PubMed:24636949}.
Subcellular Location Isoform 3: Nucleus, nucleoplasm. Nucleus, nucleolus. Nucleus, nuclear pore complex. Note=Colocalizes with RNA polymerase II in the nucleus. Colocalizes with RNA polymerase I in nucleoli (By similarity). In the nucleolus, is localized predominantly in dense fibrillar component (DFC) and in granular component (GC). Accumulates strongly in DFC and GC during activation of transcription. Colocalizes with transcription sites. Colocalizes in the granular cortex at the periphery of the nucleolus with RPS6. Colocalizes in nucleoplasm with RPS6 and actin that are in contact with RNP particles. Colocalizes with RPS6 at the nuclear pore level. {ECO:0000250}.

Human Myosin 1C full length protein - ab158939 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158939 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Myosin 1C protein fragment - ab158940 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158940 on a 12.5% SDS-PAGE stained with Coomassie Blue.

MYO1C Antibody Blocking Peptide - LS-E8215 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Myosin 1C Protein - H00004641-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human Myosin 1C Protein - H00004641-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human
Recombinant Human Myosin 1C Protein [H00004641-P01] - 12.5% SDS-PAGE Stained with Coomassie Blue.

Myosin 1C Peptide - P2030 from Novus Biologicals

Category Peptide
Species Human

Myosin-1C-MYO1C-Antibody-C-term-Blocking-peptide - BP6372b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Myosin Ic Blocking Peptide - 33R-6834 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Myosin-Ic - H00004641-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

Myosin-Ic - H00004641-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Myosin-Ic - H00004641-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

MYO1C fusion protein - ag11949 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

MYO1C fusion protein - Ag11970 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Myosin IC (MYO1C) - RPD432Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Myosin IC (MYO1C) - RPD432Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat

Recombinant Myosin IC (MYO1C) - RPD432Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Myosin IE (MYO1E) - RPD434Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Unconventional myosin-Ic(MYO1C) ,partial - CSB-YP015340HU CSB-EP015340HU CSB-BP015340HU CSB-MP015340HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Myosin IC Protein (Recombinant) - abx168169 from Abbexa

Category Protein
Source Human
Species Human

Myosin 1C Recombinant Protein Antigen - NBP1-87745PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Myosin-1C-MYO1C-Antibody-Center-Blocking-peptide - BP6372c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MYO1C Peptide, Human - M34GP10025H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Recombinant Myosin IC (MYO1C) - RPU52470 from Biomatik

Category Protein
Prices $188.00, $385.00, $589.00, $701.92
Sizes 10 µg, 50 µg, 100 µg, 200 µg
Source E.coli
Species Human

MYO1C Recombinant Protein (OPCD05538) - OPCD05538 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human

Myosin IC, Recombinant Protein - MBS2029936 from MyBioSource

Category Protein
Prices $185.00, $385.00, $595.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Human
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