CXCR2

Gene Symbol	CXCR2
Entrez Gene	3579
Alt Symbol	CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB
Species	Human
Gene Type	protein-coding
Description	chemokine (C-X-C motif) receptor 2
Other Description	C-X-C chemokine receptor type 2|CXC-R2|CXCR-2|CXCR2 gene for IL8 receptor type B|GRO/MGSA receptor|IL-8 receptor type 2|IL-8R B|chemokine (CXC) receptor 2|high affinity interleukin-8 receptor B|interleukin 8 receptor B|interleukin 8 receptor type 2|interleukin 8 receptor, beta|interleukin-8 receptor type B
Swissprots	P25025 Q8IUZ1 Q9P2T6 Q9P2T7
Accessions	AAA15417 AAB24742 AAB60656 AAC14460 AAT97985 AAY24026 BAA92295 BAA92296 CBX54347 EAW70589 P25025 AJ710879 AK290906 BAF83595 AK312664 BAG35546 BC037961 AAH37961 DA670033 DA674925 DQ893661 ABM84587 DQ895671 ABM86597 L19593 AAB59437 M73969 AAA83148 M94582 AAA36108 U11872 AAA64380 U11873 AAA64381 U11874 AAA64382 U11875 AAA64383 U11876 AAA64384 U11877 AAA64385 U11878 AAA64386 XM_005246530 XP_005246587 NM_001168298 NP_001161770 NM_001557 NP_001548
Function	Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction, Epithelial cell signaling in Helicobacter pylori infection, Endocytosis, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CXCR2 full length protein - ab112309 from Abcam Category Protein Source Wheat germ Species Human

Human CXCR2 peptide - ab24280 from Abcam Category Peptide

CXCR2 Antibody Blocking Peptide - LS-E27835 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CXCR2 Antibody Blocking Peptide - LS-E29309 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CXCR2 Antibody Blocking Peptide - LS-E29317 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CXCR2 Antibody Blocking Peptide - LS-E29313 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

CXCR2 Antibody Blocking Peptide - LS-E15446 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CXCR2/IL-8 RB Protein - H00003579-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IL8RB Protein Lysate (APL10343) - APL10343 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

IL8RB Blocking Peptide - 33R-5899 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CXCR2 Peptide - AC21-2645-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD182 / IL8RB - H00003579-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

CD182 / IL8RB - H00003579-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD182 / IL8RB - H00003579-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CD182 / IL8RB Control Peptide - AP09955CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

CD182 / IL8RB Control Peptide - AP09956CP-N from Acris Antibodies Category Peptide Prices $390.00 Sizes 250 µg

IL8RB fusion protein - Ag14670 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

IL8RB fusion protein - Ag14982 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human CXCR2 - CXCR2-26726TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human IL8RB, GST-tagged - IL8RB-14213H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Interleukin 8 Receptor Beta (IL8Rb) - RPC006Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Interleukin 8 Receptor Beta (IL8Rb) - RPC006Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Interleukin 8 Receptor Beta (IL8Rb) - RPC006Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Interleukin 8 Receptor Beta (IL8Rb) - RPC006Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

ChemiScreen™ CXCR2 Membrane Preparation - HTS002M from EMD Millipore Prices $596.00 Sizes 200 assays

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