ZBTB16

Gene Symbol	ZBTB16
Entrez Gene	7704
Alt Symbol	PLZF, ZNF145
Species	Human
Gene Type	protein-coding
Description	zinc finger and BTB domain containing 16
Other Description	promyelocytic leukaemia zinc finger|zinc finger and BTB domain-containing protein 16|zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)|zinc finger protein PLZF
Swissprots	Q05516 Q8TAL4
Accessions	AAC32847 AAC32848 AAC32849 AAC60590 AAD03619 EAW67241 EAW67242 Q05516 AB208916 BAD92153 AK126422 BC026902 AAH26902 BC029812 AAH29812 BM969145 BX648973 EU446725 ABZ92254 Z19002 CAA79489 XM_005271658 XP_005271715 XM_011542971 XP_011541273 NM_001018011 NP_001018011 NM_006006 NP_005997
Function	Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269|PubMed:14528312}.
Subcellular Location	Nucleus.
Tissue Specificity	Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
Top Pathways	Acute myeloid leukemia, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Plzf peptide - ab39353 from Abcam Category Peptide

Human Plzf protein fragment - ab125992 from Abcam Category Protein Source E. coli Species Human

ZBTB16 / PLZF Antibody Blocking Peptide - LS-E8368 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZBTB16 / PLZF Antibody Blocking Peptide - LS-E7424 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZBTB16 / PLZF Antibody Blocking Peptide - LS-E13942 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PLZF Protein - H00007704-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PLZF Peptide - P1702 from Novus Biologicals Category Peptide Species Human

Phospho-ZBTB16Y334-Antibody-Blocking-peptide - BP3575a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

PLZF-Antibody-C-term-Blocking-Peptide - BP6664b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZBTB16 - H00007704-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ZBTB16 - H00007704-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PLZF fusion protein - ag3783 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ZBTB16 (transcript variant 1) - TP306745 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PLZF Recombinant Protein Antigen - NBP1-80894PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZBTB16 Peptide, Human - M34GP17670H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant PLZF Protein - 31545 from ActiveMotif Category Protein Prices $395.00, $3,500.00 Sizes 20 µg, 1 mg Source Baculovirus Species Human

PLZF fusion protein - Ag27547 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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