UCN

Gene Symbol UCN
Entrez Gene 7349
Alt Symbol UI, UROC
Species Human
Gene Type protein-coding
Description urocortin
Other Description prepro-urocortin|urocortin, preproprotein
Swissprots P55089 Q6FG64
Accessions AAC24204 AAY24297 EAX00605 P55089 BC104470 AAI04471 BC104471 AAI04472 CR542244 CAG47040 NM_003353 NP_003344
Function Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563). Plays a role in the establishment of normal hearing thresholds (By similarity). Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity). {ECO:0000250|UniProtKB:P55090, ECO:0000250|UniProtKB:P81615, ECO:0000269|PubMed:8612563}.
Subcellular Location Secreted.
Tissue Specificity Keratinocytes in epidermis and the outer and inner root sheaths of hair follicles, epithelium of sebaceous and sweat glands, erector pili muscle, cutaneous blood vessel walls, cutaneous nerves and dermal mononuclear cells (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) (at protein level). Expressed in pituitary and adrenal glands (PubMed:10690896). Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481). {ECO:0000269|PubMed:10690896, ECO:0000269|PubMed:15531481}.

urocortin CRISPR/Cas9 KO Plasmid (h) - sc-403604 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin HDR Plasmid (h) - sc-403604-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin Double Nickase Plasmid (h) - sc-403604-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin Double Nickase Plasmid (h2) - sc-403604-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin CRISPR Activation Plasmid (h) - sc-403604-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin CRISPR Activation Plasmid (h2) - sc-403604-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin Lentiviral Activation Particles (h) - sc-403604-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin Lentiviral Activation Particles (h2) - sc-403604-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

urocortin siRNA (h) - sc-39399 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

urocortin shRNA Plasmid (h) - sc-39399-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

urocortin shRNA (h) Lentiviral Particles - sc-39399-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN22442 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22442 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

UCN siRNA (Human) - CRH5024 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UCN - MBS8221398 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UCN (NM_003353.2) - SHH439840 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human UCN(NM_003353.2) - SHL104736 from Creative biogene

Category siRNA
Species Reactivities Human

UCN shRNA Plasmid (Human) - CHH5024 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UCN miRNA 3'UTR clone - MiUTR1H-10978 from Creative biogene

Species Reactivities Human
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