Gene Symbol | ARIH1 |
---|---|
Entrez Gene | 25820 |
Alt Symbol | ARI, HARI, HHARI, UBCH7BP |
Species | Human |
Gene Type | protein-coding |
Description | ariadne RBR E3 ubiquitin protein ligase 1 |
Other Description | ARI-1|E3 ubiquitin-protein ligase ARIH1|H7-AP2|MOP-6|ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1|ariadne, Drosophila, homolog of|monocyte protein 6|protein ariadne-1 homolog|ubcH7-binding protein|ubcM4-interacting protein|ubiquitin-conjugating enzyme E2-binding protein 1 |
Swissprots | Q9UP39 Q9H3T6 O76026 B2R6U3 Q9UEN0 Q9Y4X5 |
Accessions | CAH05382 EAW77907 EAW77908 Q9Y4X5 AB014774 BAB19786 AB209432 BAD92669 AF072832 AAD28088 AJ009771 CAA08817 AJ130976 CAA10274 AJ243190 CAB45870 AK000336 AK312715 BAG35590 AL117650 BC051877 AAH51877 BX641117 XM_011521438 XP_011519740 XM_011521439 XP_011519741 NM_005744 NP_005735 |
Function | E3 ubiquitin-protein ligase, which catalyzes polyubiquitination of target proteins together with ubiquitin- conjugating enzyme E2 UBE2L3. May play a role in protein translation by mediating polyubiquitination of EIF4E2, leading to its subsequent degradation. Acts as the ligase involved in ISGylation of EIF4E2. {ECO:0000269|PubMed:14623119, ECO:0000269|PubMed:15236971, ECO:0000269|PubMed:17289916, ECO:0000269|PubMed:21532592}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11278816}. Note=Mainly cytoplasmic. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10521492}. |
ARIH1 Antibody Blocking Peptide - LS-E25486 from LifeSpan Bioscience
|
||||||||||
ARIH1 Antibody Blocking Peptide - LS-E15845 from LifeSpan Bioscience
|
||||||||||
ARIH1/HHARI blocking peptide - GTX89873-PEP from GeneTex
|
||||||||||
ARIH1 Blocking Peptide - 33R-1555 from Fitzgerald
|
||||||||||
ARIH1 Peptide - AC21-0315-P from Abcore
|
||||||||||
ARIH1 Peptide - 45-282P from ProSci
|
||||||||||
ARIH1 fusion protein - Ag6760 from Proteintech Group
|
||||||||||
ARIH1 fusion protein - Ag6584 from Proteintech Group
|
||||||||||
Recombinant Human E3 ubiquitin-protein ligase ARIH1(ARIH1) - CSB-YP896897HU CSB-EP896897HU CSB-BP896897HU CSB-MP896897HU from Cusabio
|
||||||||||
ARIH1/HHARI, Peptide - MBS425220 from MyBioSource
|
||||||||||
ARIH1 Recombinant Protein Antigen - NBP1-88984PEP from Novus Biologicals
|
||||||||||
ARIH1-UbcH7-BP-Antibody-C-term-Blocking-peptide - BP2100b from Abgent, a WuXi AppTec company
|
||||||||||
ARIH1 Peptide, Human - M34GP00913H from Creative Peptides
|
||||||||||
ARIH1 Recombinant Protein Antigen - NBP2-57888PEP from Novus Biologicals
|
||||||||||
E3 ubiquitin-protein ligase ARIH1 (ARIH1), Recombinant Protein - MBS1439772 from MyBioSource
|