CSNK2A2

Gene Symbol	CSNK2A2
Entrez Gene	1459
Alt Symbol	CK2A2, CSNK2A1
Species	Human
Gene Type	protein-coding
Description	casein kinase 2, alpha prime polypeptide
Other Description	CK II alpha'|casein kinase II subunit alpha'
Swissprots	P19784
Accessions	EAW82969 P19784 AI150700 AK090752 AK125922 BC008812 AAH08812 DQ893025 ABM83951 DQ896269 ABM87268 M55268 AAA51548 XM_005255800 XP_005255857 XM_005255801 XP_005255858 NM_001896 NP_001887
Function	Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activat
Top Pathways	Wnt signaling pathway, Adherens junction, Tight junction, Ribosome biogenesis in eukaryotes, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CSNK2A2 overexpression lysate - LY400706 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CSNK2A2 293 Cell Lysate - 400686 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CKII alpha prime polypeptide Overexpression Lysate (Native) - NBL1-09537 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CSNK2A2 Over-expression Lysate Product - GWB-D205C4 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human CSNK2A2 / CK2A2 Insect Cell Lysate (WB positive control) - 11018-HNCBL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human CSNK2A2 / CK2A2 Insect Cell Lysate (WB positive control) - 11018-H20BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

CKII alpha prime polypeptide Overexpression Lysate (Denatured) - H00001459-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Human CSNK2A2 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175286 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Human CSNK2A2 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb174998 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human CSNK2A2 Knockdown Stable Cell Line - CSC-DC003725 from Creative biogene Category Cell Line Species Human

Search more