CSNK2A2

Gene Symbol	CSNK2A2
Entrez Gene	1459
Alt Symbol	CK2A2, CSNK2A1
Species	Human
Gene Type	protein-coding
Description	casein kinase 2, alpha prime polypeptide
Other Description	CK II alpha'|casein kinase II subunit alpha'
Swissprots	P19784
Accessions	EAW82969 P19784 AI150700 AK090752 AK125922 BC008812 AAH08812 DQ893025 ABM83951 DQ896269 ABM87268 M55268 AAA51548 XM_005255800 XP_005255857 XM_005255801 XP_005255858 NM_001896 NP_001887
Function	Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activat
Top Pathways	Wnt signaling pathway, Adherens junction, Tight junction, Ribosome biogenesis in eukaryotes, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CKII alpha prime polypeptide full length protein - ab105125 from Abcam Category Protein Prices $302.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Active human CKII alpha prime polypeptide full length protein - ab90035 from Abcam Category Protein Prices $239.00 Sizes 10 µg Source E. coli Species Human

Human CKII alpha prime polypeptide full length protein - ab131679 from Abcam Category Protein Source E. coli Species Human

CSNK2A2 Antibody Blocking Peptide - LS-E2719 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CKII alpha prime polypeptide Recombinant Protein - H00001459-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CKII alpha prime polypeptide Partial Recombinant Protein - H00001459-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CKII alpha prime polypeptide Protein - NBP2-22736 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

CKII alpha prime polypeptide Recombinant Protein - P4668 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

Human CSNK2A2 protein - orb138639 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source Baculovirus-Insect Cells Species Human

Human CSNK2A2 His GST tag protein - orb84077 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 20 μg, 50 μg Source Insect Species Human

CSNK2A2 protein (His tag) - 80R-2443 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

CSNK2A2 / CK2A2 (1-350, His-tag) - AR50523PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

CSNK2A2 / CK2A2 (1-350, His-tag) - AR50523PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

CSNK2A2 / CK2A2 - H00001459-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CSNK2A2 / CK2A2 - H00001459-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CSNK2A2 / CK2A2 - H00001459-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CSNK2A2 / CK2A2 - H00001459-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CSNK2A2 / CK2A2 - P4668 from Acris Antibodies Category Protein Prices $1,380.00 Sizes 100 µg Species Human

CSNK2A2 / CK2A2 - P5527 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

CSNK2A2, 1-350aa, Human, His tag, E.coli - 01-P1699 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

CSNK2A2 fusion protein - ag0877 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant CK2α2 protein - 31150 from ActiveMotif Category Protein Prices $390.00 Sizes 10 µg Source E. coli Species Human

CSNK2A2, 1-350aa, Recombinant Protein - GWB-P0339A from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human CSNK2A2 - CSNK2A2-169H from Creative Biomart Category Protein Source E. coli.

Recombinant Human CSNK2A2, GST-tagged - CSNK2A2-682H from Creative Biomart Category Protein Source Insect cells .

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