FLNA

Gene Symbol	FLNA
Entrez Gene	2316
Alt Symbol	ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Species	Human
Gene Type	protein-coding
Description	filamin A, alpha
Other Description	actin binding protein 280|alpha-filamin|endothelial actin-binding protein|filamin-1|filamin-A|non-muscle filamin
Swissprots	Q8NF52 P21333 E9KL45 Q5HY55 Q5HY53
Accessions	AAA92644 AIG59194 CAA49687 CAA49690 CCH22601 CCH22602 EAW72744 EAW72745 EAW72746 EAW72747 EAW72748 P21333 AB191259 BAD52435 AB191260 BAD52436 AB371574 BAG48303 AB371575 BAG48304 AB371576 BAG48305 AB371577 BAG48306 AB371578 BAG48307 AB371579 BAG48308 AB593010 BAJ83965 AK074048 BAB84874 AK090427 BAC03408 AK125630 AK300165 BAG61947 AK304255 BAG65121 AL050396 AL157419 BC014654 AAH14654 BC028089 BC041179 AAH41179 BC067111 AAH67111 BC109289 AAI09290 BP235228 GU727643 ADU87644 X53416 CAA37495 XM_011531127 XP_011529429 XM_011531128 XP_011529430 XM_011531129 XP_011529431 XM_011531130 XP_011529432 XM_011531131 XP_011529433 NM_001110556 NP_001104026 NM_001456 NP_001447
Function	Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. {ECO:0000250, ECO:0000269|PubMed:22121117}.
Subcellular Location	Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Tissue Specificity	Ubiquitous.
Top Pathways	Focal adhesion, MAPK signaling pathway, Salmonella infection, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat FLNA / Filamin A ELISA Kit (Cell-Based ELISA) - LS-F1992 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 1.88-120 ng/ml

Human FLNA / Filamin A ELISA Kit (Sandwich ELISA) - LS-F9142 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 1.88 ng/ml Range 1.88-120 ng/ml

Rabbit anti-Filamin A Antibody, Affinity Purified - PLA0168 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Filamin A Alpha (FLNa), Human, ELISA Kit - SEC214Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.72ng/mL Range 1.88-120ng/mL

Filamin A, Alpha, Human, ELISA Kit - E01F0098 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Filamin A, Alpha, FLNa, Human, ELISA Kit - E-EL-H2095 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Filamin A, FLNa, Mouse, ELISA Kit - E-EL-M0507 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Filamin A, Alpha, FLNa, Rabbit, ELISA Kit - E-EL-RB0267 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Filamin A, Alpha, FLNa, Chicken, ELISA Kit - E-EL-Ch1218 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Filamin A, Alpha, FLNa, Porcine, ELISA Kit - E-EL-P0572 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Filamin A, Alpha, FLNa, Guinea Pig, ELISA Kit - E-EL-GP0750 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Filamin A, Alpha, FLNa, Monkey, ELISA Kit - E-EL-MK2224 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human FLNa ELISA Kit - HF0105 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine FLNa ELISA Kit - AF0105 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Filamin B, Beta, ELISA Kit - MBS028740 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS007285 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS033410 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS034710 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS046241 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS030883 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS026792 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS085676 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS036782 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS093615 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Filamin B, Beta, ELISA Kit - MBS025794 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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