FLNA

Gene Symbol	FLNA
Entrez Gene	2316
Alt Symbol	ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Species	Human
Gene Type	protein-coding
Description	filamin A, alpha
Other Description	actin binding protein 280|alpha-filamin|endothelial actin-binding protein|filamin-1|filamin-A|non-muscle filamin
Swissprots	Q8NF52 P21333 E9KL45 Q5HY55 Q5HY53
Accessions	AAA92644 AIG59194 CAA49687 CAA49690 CCH22601 CCH22602 EAW72744 EAW72745 EAW72746 EAW72747 EAW72748 P21333 AB191259 BAD52435 AB191260 BAD52436 AB371574 BAG48303 AB371575 BAG48304 AB371576 BAG48305 AB371577 BAG48306 AB371578 BAG48307 AB371579 BAG48308 AB593010 BAJ83965 AK074048 BAB84874 AK090427 BAC03408 AK125630 AK300165 BAG61947 AK304255 BAG65121 AL050396 AL157419 BC014654 AAH14654 BC028089 BC041179 AAH41179 BC067111 AAH67111 BC109289 AAI09290 BP235228 GU727643 ADU87644 X53416 CAA37495 XM_011531127 XP_011529429 XM_011531128 XP_011529430 XM_011531129 XP_011529431 XM_011531130 XP_011529432 XM_011531131 XP_011529433 NM_001110556 NP_001104026 NM_001456 NP_001447
Function	Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. {ECO:0000250, ECO:0000269|PubMed:22121117}.
Subcellular Location	Cytoplasm, cell cortex. Cytoplasm, cytoskeleton.
Tissue Specificity	Ubiquitous.
Top Pathways	Focal adhesion, MAPK signaling pathway, Salmonella infection, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FLNA protein full length protein - ab131760 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human Filamin A Protein - H00002316-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Filamin-A - H00002316-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Filamin-A - H00002316-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FLNA fusion protein - ag1581 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Filamin - GWB-92A77D from Genway Biotech Category Protein Prices $75.00, $165.00, $1,670.00 Sizes 10 μg, 50 μg, 1000 μg

Recombinant Human FLNA, His-tagged - FLNA-28906TH from Creative Biomart Category Protein Source E. coli

Recombinant Human FLNA, GST-tagged - FLNA-289H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Filamin A Alpha (FLNa) - RPC214Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Filamin A Blocking Peptide - CBP1434 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Rabbit

Filamin A (pS2152) Blocking Peptide - CBP3221 from Cohesion Biosciences Category Peptide Prices $150.00, $450.00 Sizes 1 mg, 5 mg Species Human, Rat

Filamin 1 (R2146) Peptide - BS1128P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

p-Filamin 1 (S2152) Peptide - BS4075P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Filamin A Alpha (FLNa) - RPC214Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Filamin-A(FLNA) ,partial - CSB-YP008724HU CSB-EP008724HU CSB-BP008724HU CSB-MP008724HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FLNA Peptide - abx164764 from Abbexa Category Peptide Species Human, Mouse

Filamin-A (transcript variant 1) - TP326488 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

filamin A, Peptide - MBS428454 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Bovine

Recombinant Human FLNA protein, MYC/DDK-tagged - FLNA-185H from Creative Biomart Category Protein Source HEK293 Species Human

Filamin A Recombinant Protein Antigen - NBP1-90284PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Filamin A Protein - NBP1-90283PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

FLNA-Antibody-Y1046-Blocking-Peptide - BP7770a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-FLNAS2522-Antibody-Blocking-peptide - BP3401a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-FLNAS2152-Antibody-Blocking-peptide - BP3379a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-FLNAY1046-Antibody-Blocking-peptide - BP3528a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

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