NCR2

Gene Symbol	NCR2
Entrez Gene	9436
Alt Symbol	CD336, LY95, NK-p44, NKP44, dJ149M18.1
Species	Human
Gene Type	protein-coding
Description	natural cytotoxicity triggering receptor 2
Other Description	NK cell activating receptor (NKp44)\|NK cell-activating receptor\|lymphocyte antigen 95 (activating NK-receptor; NK-p44)\|lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44)\|natural killer cell p44-related protein
Swissprots	Q9H562 O95944 Q9UMT2 Q9H563 Q9UMT1 Q9H564
Accessions	EAX04039 EAX04040 EAX04041 EAX04042 O95944 AJ010099 CAB52289 AJ010100 CAB52290 BC166647 AAI66647 NM_001199509 NP_001186438 NM_001199510 NP_001186439 NM_004828 NP_004819
Function	Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. {ECO:0000269\|PubMed:10049942}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. {ECO:0000269\|PubMed:10049942}.
Top Pathways	Natural killer cell mediated cytotoxicity

NKp44 (2.29) - sc-53597 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

NKp44 (3.43) - sc-53598 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

NKp44 (8F12) - sc-59342 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	50 µg/500 µl
Host	Mouse
Clonality	Monoclonal

NKp44 (8F12): sc-59342. Western blot analysis of recombinant human NKp30 (A), NKp44 (B) and NKp46 (C).

NKp44 (6D613) - sc-71709 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

NKp44 (P44-8) - sc-73401 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

Anti-NCR2 antibody [8F12] - ab25911 from Abcam

Prices	$370.00
Sizes	50 µl
Host	Mouse
Clonality	Monoclonal
Clone	8F12

All lanes : Anti-NCR2 antibody [8F12] (ab25911) at 1/1000 dilutionLane 1 : recombinant human NKp30Lane 2 : recombinant human NCR2 (NKp44) fragment aa 19-130. (~16kDa)Lane 3 : recombinant human NKp46Lysates/proteins at 0.02 µg per lane.Secondarygoat anti-mouse secondary antibody conjugated to HRP

Anti-NCR2 antibody [EPR5060(2)] - ab133668 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5060(2)

All lanes : Anti-NCR2 antibody [EPR5060(2)] (ab133668) at 1/10000 dilutionLane 1 : Humam lymph node lysateLane 2 : K562 cell lysateLane 3 : Jurkat cell lysateLane 4 : HuT-78 cell lysateLane 5 : Molt-4 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP conjugate at 1/2000 dilution

Anti-NCR2 antibody [EPR5060(2)] (HRP) - ab199525 from Abcam

Prices	$425.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5060(2)

Lane 1 : Lane 2 : Lane 3 : Lane 4 : Lane 1 : Lymph node (Human) Tissue Lysate - adult normal tissue with Anti-NCR2 antibody [EPR5060(2)] (HRP) (ab199525)Lane 2 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell Lysate with Anti-NCR2 antibody [EPR5060(2)] (HRP) (ab199525)Lane 3 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate with Anti-NCR2 antibody [EPR5060(2)] (HRP) (ab199525)Lane 4 : MOLT4 (Human acute lymphoblastic leukemia cell line) Whole Cell Lysate with Anti-NCR2 antibody [EPR5060(2)] (HRP) (ab199525)Lysates/proteins at 10 µg per lane.Blocking peptides at 1/5000 dilution per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-NKP44 Antibody (aa19-130) - LS-C37674 from LifeSpan Bioscience

Prices	$355.00
Sizes	50 µl
Host	Mouse
Clonality	Monoclonal

Anti-NCR2 / NKP44 Antibody (clone P44-8) - LS-C40794 from LifeSpan Bioscience

Prices	$235.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	P44-8

Anti-NCR2 / NKP44 Antibody (PE) - LS-C126036 from LifeSpan Bioscience

Prices	$530.00
Sizes	100 tst
Host	Mouse
Clonality	Monoclonal

Anti-NKP44 Antibody (aa19-130, clone 8F12) - LS-C93770 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	8F12

Human recombinant proteins, NKp30, NKp44, and NKp46 (each 20 ng per well) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NKp44 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1: recombinant human NKp30; Lane 2: recombinant human NKp44; Lane 3: recombinant human NKp46.

Anti-NKP44 Antibody (Internal, clone EPR5060(2)) - LS-C154614 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR5060(2)

Immunofluorescent staining of K562 cells using anti-NCR2 antibody.

NKp44/NCR2 Antibody (253415) [Unconjugated] - MAB22491 from Novus Biologicals

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clonality	Monoclonal
Clone	253415

Mouse Anti-Human NKp44/NCR2 Monoclonal Antibody (Catalog # MAB22491) induces IFN-gamma secretion in human natural killer (NK) cells activated with 500 ng/mL Recombinant Human IL-2 (Catalog # 202-IL), in a dose-dependent manner, as measured using the Quantikine Human IFN-gamma ELISA Kit (Catalog # DIF50). The ED50 for this effect is typically 0.05‑0.2 μg/mL.

NKp44/NCR2 Antibody - AF2249 from Novus Biologicals

Prices	$99.00, $359.00
Sizes	25 µg, 100 µg
Host	Goat
Clonality	Polyclonal

Human NKp44 Antigen Affinity-purified Polyclonal Antibody induces IFN-gamma secretion in human natural killer (NK) cells activated with 1,000 U/mL Recombinant Human IL-2 (Catalog # 202-IL), in a dose-dependent manner, as measured using the Quantikine Human IFN‑ gamma ELISA Kit (Catalog # DIF50). The ED50 for this effect is typically 0.2‑0.6 μg/mL.

NKp44/NCR2 Antibody (253422) - MAB2249 from Novus Biologicals

Prices	$99.00, $249.00
Sizes	25 µg, 100 µg
Host	Mouse
Clonality	Monoclonal
Clone	253422

NKp44/NCR2 Antibody - NBP2-38103 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: NKp44/NCR2 Antibody [NBP2-38103] - Staining of human colon shows positivity in subsets of leukocytes.

NKp44/NCR2 Antibody (8F12) - NBP1-04322 from Novus Biologicals

Prices	$309.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	8F12

Western Blot: NCR2 Antibody (8F12) [NBP1-04322] - Human recombinant proteins, NKp30, NKp44, and NKp46 (each 20ng per well) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NKp44 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Arrow indicates human recombinant protein NKp44 (residues 19~130).

NKp44/NCR2 Antibody (253415) [Allophycocyanin] - FAB22491A-100 from Novus Biologicals

Host	Mouse
Clonality	Monoclonal
Clone	253415

NKp44/NCR2 Antibody (253415) [Allophycocyanin] - FAB22491A-025 from Novus Biologicals

Host	Mouse
Clonality	Monoclonal
Clone	253415

NKp44/NCR2 Antibody [Biotin] - BAF2249 from Novus Biologicals

Prices	$390.00
Sizes	50 µg
Host	Goat
Clonality	Polyclonal

NKp44/NCR2 Antibody (253415) [PE] - FAB22491P-100 from Novus Biologicals

Host	Mouse
Clonality	Monoclonal
Clone	253415

NKp44/NCR2 Antibody (253415) [PE] - FAB22491P-025 from Novus Biologicals

Host	Mouse
Clonality	Monoclonal
Clone	253415

NCR2 Polyclonal Antibody - bs-2420R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin embedded human laryngocarcinoma labeled with Anti CD336/NKp44/NCR2 Polyclonal Antibody, Unconjugated (bs-2420R) at 1:400 followed by conjugation to the secondary antibody and DAB staining.

Anti-NCR2 antibody produced in rabbit - SAB4301069 from Sigma-Aldrich

Prices	$230.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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