SMEK2

Gene Symbol SMEK2
Entrez Gene 57223
Alt Symbol FLFL2, PP4R3B, PSY2, smk1
Species Human
Gene Type protein-coding
Description SMEK homolog 2, suppressor of mek1 (Dictyostelium)
Other Description serine/threonine-protein phosphatase 4 regulatory subunit 3B
Swissprots Q9P2G0 Q9BRK2 Q9H913 Q9BQJ0 Q6P9B0 Q5MIZ7 Q86XB8
Accessions AAY24270 EAX00090 EAX00091 EAX00092 EAX00093 EAX00094 EAX00095 EAX00096 Q5MIZ7 AB037808 BAA92625 AK023148 BAB14430 AK026437 AK056036 AK056503 AK098321 AK296481 BAG59121 AL122106 AL136556 CAB66491 AY825268 AAV97750 AY825269 AAV97751 BC006215 AAH06215 BC032531 BC045714 AAH45714 BC060855 AAH60855 BE535214 DA392286 DB261776 XM_005264442 XP_005264499 XM_005264444 XP_005264501 XM_005264445 XP_005264502 XM_005264446 XP_005264503 XM_005264447 XP_005264504 XM_005264448 XP_005264505 XM_011533002 XP_011531304 NM_001122964 NP_001116436 NM_001282850 NP_001269779 NM_020463 NP_065196
Function Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18487071}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18487071}. Nucleus {ECO:0000269|PubMed:18487071}. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions.
Tissue Specificity Moderately expressed in tissues and specific brain regions examined. {ECO:0000269|PubMed:10718198}.
Top Pathways Glucagon signaling pathway

SMEK2 (D-13) - sc-169368 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SMEK2 (N-14) - sc-169370 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SMEK2 antibody - ab70622 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling SMEK2 with ab70622 at 1/200 (1µg/ml). Detection: DAB.

Anti-SMEK2 antibody - ab123660 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SMEK2 antibody (ab123660) at 1/100 dilution + A549 cell lysate at 35 µg

Anti-SMEK2 antibody - ab70620 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SMEK2 by Western Blot of Immunprecipitate. Staining of SMEK2 (approximately 98kDa) in HeLa whole cell lysates immunoprecipitated using ab70620 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Another SMEK2 antibody was used for immunoblotting. Detection: Chemiluminescence with an exposure time of 10 seconds.

Anti-SMEK2 antibody - ab92404 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed, paraffin-ambedded section of human breast carcinoma stained with ab92404 used at a dilution of 1:250. Detection: DAB staining.

Anti-SMEK2 Antibody (C-Terminus) - LS-C91598 from LifeSpan Bioscience

Prices $545.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa720-748, AP) - LS-C217622 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa720-748, APC) - LS-C217623 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa720-748, FITC) - LS-C217624 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa720-748, Biotin) - LS-C217625 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa720-748, Azide-free, HRP) - LS-C217626 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa720-748, PE) - LS-C217627 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa711-760) - LS-C135445 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SMEK2 antibody LS-C135445 Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.

Anti-SMEK2 Antibody (aa125-175) - LS-C287689 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa719-748) - LS-C325204 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 Antibody (aa720-748) - LS-C161315 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SMEK2 Antibody western blot of A549 cell line lysates (35 ug/lane). The SMEK2 antibody detected the SMEK2 protein (arrow).

Anti-SMEK2 Antibody (Internal) - LS-C345549 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of P4R3B Antibody with human Stomach Tumor lysate.

Anti-SMEK2 Antibody (C-Terminus) - LS-C286690 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PPP4R3 Beta by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Beta used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.

Anti-SMEK2 Antibody (C-Terminus) - LS-C287690 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PPP4R3 Beta by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Beta used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

SMEK2 Antibody - NB100-2881 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SMEK2 Antibody - NBP1-83882 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PP4R3B Polyclonal Antibody - bs-8328R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SMEK2 antibody produced in rabbit - HPA001233 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SMEK2: <B>Cat. No. HPA001233</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human small intestinal tissue showing nuclear staining of glandular cells.

ANTI-SMEK2 (C-TERM) antibody produced in rabbit - SAB1304494 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SMEK2 (C-term): <B>Cat. No. SAB1304494</B>: SMEK2 Antibody (C-term) western blot analysis in A549 cell line lysates (35 μg/lane).
Search more