SMEK2

Gene Symbol SMEK2
Entrez Gene 57223
Alt Symbol FLFL2, PP4R3B, PSY2, smk1
Species Human
Gene Type protein-coding
Description SMEK homolog 2, suppressor of mek1 (Dictyostelium)
Other Description serine/threonine-protein phosphatase 4 regulatory subunit 3B
Swissprots Q9P2G0 Q9BRK2 Q9H913 Q9BQJ0 Q6P9B0 Q5MIZ7 Q86XB8
Accessions AAY24270 EAX00090 EAX00091 EAX00092 EAX00093 EAX00094 EAX00095 EAX00096 Q5MIZ7 AB037808 BAA92625 AK023148 BAB14430 AK026437 AK056036 AK056503 AK098321 AK296481 BAG59121 AL122106 AL136556 CAB66491 AY825268 AAV97750 AY825269 AAV97751 BC006215 AAH06215 BC032531 BC045714 AAH45714 BC060855 AAH60855 BE535214 DA392286 DB261776 XM_005264442 XP_005264499 XM_005264444 XP_005264501 XM_005264445 XP_005264502 XM_005264446 XP_005264503 XM_005264447 XP_005264504 XM_005264448 XP_005264505 XM_011533002 XP_011531304 NM_001122964 NP_001116436 NM_001282850 NP_001269779 NM_020463 NP_065196
Function Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18487071}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18487071}. Nucleus {ECO:0000269|PubMed:18487071}. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions.
Tissue Specificity Moderately expressed in tissues and specific brain regions examined. {ECO:0000269|PubMed:10718198}.
Top Pathways Glucagon signaling pathway

SMEK2 CRISPR/Cas9 KO Plasmid (h) - sc-412783 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 HDR Plasmid (h) - sc-412783-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 Double Nickase Plasmid (h) - sc-412783-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 Double Nickase Plasmid (h2) - sc-412783-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 CRISPR Activation Plasmid (h) - sc-412783-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 CRISPR Activation Plasmid (h2) - sc-412783-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 Lentiviral Activation Particles (h) - sc-412783-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 Lentiviral Activation Particles (h2) - sc-412783-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMEK2 siRNA (h) - sc-94851 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMEK2 shRNA Plasmid (h) - sc-94851-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMEK2 shRNA (h) Lentiviral Particles - sc-94851-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMEK2 RNAi - H00057223-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU083061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19787 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19787 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09502 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09502

SMEK2 siRNA (Human) - CRJ1405 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMEK2 - MBS8217095 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SMEK2 (NM_020463.2) - SHH413388 from Creative biogene

Category siRNA
Species Reactivities Human

Human SMEK2 siRNA - orb271906 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMEK2 shRNA Plasmid (Human) - CHJ1405 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SMEK2 miRNA 3'UTR clone - MiUTR3H-11179 from Creative biogene

Species Reactivities Human

SMEK2 miRNA 3'UTR clone - MiUTR3H-11180 from Creative biogene

Species Reactivities Human
Search more