| Gene Symbol |
HES5
|
| Entrez Gene |
388585
|
| Alt Symbol |
bHLHb38
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hes family bHLH transcription factor 5
|
| Other Description |
class B basic helix-loop-helix protein 38|hairy and enhancer of split 5|transcription factor HES-5
|
| Swissprots |
Q5TA89 B9DI85
|
| Accessions |
EAW56096 Q5TA89 BC087840 AAH87840 BX104111 DQ272660 ABB83829 XM_005244751 XP_005244808 XM_006724945 XP_006725008 NM_001010926 NP_001010926
|
| Function |
Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
|
| Tissue Specificity |
Expressed in fetal heart and brain tumors. {ECO:0000269|PubMed:15254753}.
|
| Top Pathways |
Notch signaling pathway
|
![Western Blot: HES5 Overexpression Lysate (Adult Normal) [NBL1-11512] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HES5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8993_HES5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11512-img0002.jpg)