Gene Symbol | HES5 |
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Entrez Gene | 388585 |
Alt Symbol | bHLHb38 |
Species | Human |
Gene Type | protein-coding |
Description | hes family bHLH transcription factor 5 |
Other Description | class B basic helix-loop-helix protein 38|hairy and enhancer of split 5|transcription factor HES-5 |
Swissprots | Q5TA89 B9DI85 |
Accessions | EAW56096 Q5TA89 BC087840 AAH87840 BX104111 DQ272660 ABB83829 XM_005244751 XP_005244808 XM_006724945 XP_006725008 NM_001010926 NP_001010926 |
Function | Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}. |
Tissue Specificity | Expressed in fetal heart and brain tumors. {ECO:0000269|PubMed:15254753}. |
Top Pathways | Notch signaling pathway |
HES5 CRISPR/Cas9 KO Plasmid (h) - sc-401625 from Santa Cruz Biotechnology
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HES5 HDR Plasmid (h) - sc-401625-HDR from Santa Cruz Biotechnology
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HES5 Double Nickase Plasmid (h) - sc-401625-NIC from Santa Cruz Biotechnology
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HES5 Double Nickase Plasmid (h2) - sc-401625-NIC-2 from Santa Cruz Biotechnology
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HES5 CRISPR Activation Plasmid (h) - sc-401625-ACT from Santa Cruz Biotechnology
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HES5 CRISPR Activation Plasmid (h2) - sc-401625-ACT-2 from Santa Cruz Biotechnology
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HES5 Lentiviral Activation Particles (h) - sc-401625-LAC from Santa Cruz Biotechnology
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HES5 Lentiviral Activation Particles (h2) - sc-401625-LAC-2 from Santa Cruz Biotechnology
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HES5 siRNA (h) - sc-72197 from Santa Cruz Biotechnology
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HES5 shRNA Plasmid (h) - sc-72197-SH from Santa Cruz Biotechnology
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HES5 shRNA (h) Lentiviral Particles - sc-72197-V from Santa Cruz Biotechnology
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HES5 RNAi - H00388585-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9996 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9996 from Sigma-Aldrich
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HES5 siRNA (Human) - CRJ7816 from Cohesion Biosciences
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HES5 - MBS8227108 from MyBioSource
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shRNA set against Human HES5 (NM_001010926.3) - SHH311717 from Creative biogene
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Human HES5 siRNA - orb278317 from Biorbyt
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HES5 shRNA Plasmid (Human) - CHJ7816 from Cohesion Biosciences
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HES5 miRNA 3'UTR clone - MiUTR3H-09168 from Creative biogene
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