HES5

Gene Symbol HES5
Entrez Gene 388585
Alt Symbol bHLHb38
Species Human
Gene Type protein-coding
Description hes family bHLH transcription factor 5
Other Description class B basic helix-loop-helix protein 38|hairy and enhancer of split 5|transcription factor HES-5
Swissprots Q5TA89 B9DI85
Accessions EAW56096 Q5TA89 BC087840 AAH87840 BX104111 DQ272660 ABB83829 XM_005244751 XP_005244808 XM_006724945 XP_006725008 NM_001010926 NP_001010926
Function Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
Tissue Specificity Expressed in fetal heart and brain tumors. {ECO:0000269|PubMed:15254753}.
Top Pathways Notch signaling pathway

HES5 (A-17) - sc-13859 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HES5 (A-17): sc-13859. Western blot analysis of HES5 expression in Sol8 nuclear extract.

HES5 (M-104) - sc-25395 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HES5 (M-104): sc-25395. Western blot analysis of HES5 expression in mouse embryo tissue extract.

HES5 (M-16) - sc-13860 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HES5 (M-16): sc-13860. Western blot analysis of HES5 expression in SK-N-MC nuclear extract.

Anti-HES5 antibody - ab25374 from Abcam

Prices $392.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab25374 staining the cortex of e14.5 mouse embryo by IHC-Fr.  The tissue was frozen and cut into 10 µm slices on a cyrostat then fixed and blocked prior to incubating with the primary antibody (diluted 1/100) for 90 minutes.  A fluorescent conjugated secondary antibody was incubated with the sample for 30 minutes.  HES-5 is shown in red in the nuclear regions; the blue staining is Hoechst nuclear counter stain.

Anti-HES5 antibody - ab203295 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded rat brain tissue labeling HES5 with ab203295 at 1/200 dilution, followed by secondary detection and DAB staining.

Anti-HES5 antibody - ab133424 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, cerebellum tissue labelling HES5 with ab133424 antibody at 2.5µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-HES5 antibody - ab202377 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HES5 antibody (ab202377) at 1/1000 dilutionLane 1 : U-87 MG cell line lysateLane 2 : SK-N-MC cell line lysateLane 3 : Human heart tissue lysateLane 4 : mouse heart tissue lysateLysates/proteins at 20 µg per lane.Secondarygoat anti-rabbit IgG H&L(HRP) at 1/10000 dilution

Anti-HES5 antibody - ab107593 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HES5 antibody (ab107593) at 7 µg/mlLane 1 : HES5 in mouse liver tissueLane 2 : HES5 in mouse liver tissue with immunizing peptide SecondaryGoat anti-rabbit Ig HRP developed using the ECL technique

Anti-HES5 antibody [EPR15578] - ab194111 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15578
Anti-HES5 antibody [EPR15578] (ab194111) at 1/10000 dilution + 293 cell lysate at 10 µgSecondaryGoat anti-rabbit IgG, (H+L), peroxidase conjugated at 1/1000 dilution

Anti-HES5 Antibody (aa28-121) - LS-C308216 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-HES5 Antibody (C-Terminus) - LS-C116386 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HES5 antibody LS-C116386 Western blot of ACHN lysate.

Anti-HES5 Antibody (N-Terminus) IHC-plus™ - LS-B12142 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-HES5 Antibody (aa81-115) - LS-C344539 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from U-87 MG, SK-N-MC cell line, human heart and mouse heart tissue (from left to right) with HES5 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

Anti-HES5 Antibody (aa83-95) IHC-plus™ - LS-B5507 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HES5 antibody IHC of mouse liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5507 concentration 5 ug/ml.

Anti-HES5 Antibody (aa1-50) - LS-C148792 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of HES5 in mouse liver tissue lysate in the 1) absence and 2) presence of immunizing peptide using LS-C148792 at 7 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution were used for this test.

Anti-HES5 Antibody (Internal) IHC-plus™ - LS-B6782 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HES5 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6782 concentration 2.5 ug/ml.

HES5 Antibody - NBP2-27174 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HES5 Antibody [NBP2-27174] - analysis of HES5 in mouse liver tissue lysate in the 1) absence and 2) presence of immunizing peptide using HES5 antibody at 7 ug/ml. goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

HES5 Antibody - NBP2-11501 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

HES5 Antibody (3C5) - H00388585-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C5

HES5 Antibody (3B6) - H00388585-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B6

HES5 Antibody - NBP2-41305 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HES5 Antibody [NBP2-41305] - Western blot analysis of HES5 in Raji cell lysate with HES5 antibody at 1 ug/ml (A) the absence and (B) the presence of blocking peptide.

Hes5 Polyclonal Antibody - bs-3767R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Hes5 Polyclonal Antibody, Unconjugated (bs-3767R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Monoclonal Anti-HES5 antibody produced in mouse - SAB1405408 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B6
<B>Immunoblotting</B><BR/>Monoclonal Anti-HES5: <B>Cat. No. SAB1405408</B>: Antibody concentration: 1 μg/mL. Specific band of ~36.3 kDa using immunogen protein lysate.

HES5 antibody - middle region (ARP50367_P050) - ARP50367_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HES5-Antibody-Center - AP20976a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from U-87 MG, SK-N-MC cell line, human heart and mouse heart tissue(from left to right), using HES5 Antibody (Center)(Cat. #AP20976a). AP20976a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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