Gene Symbol | KIAA0319 |
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Entrez Gene | 9856 |
Alt Symbol | DYLX2, DYX2, NMIG |
Species | Human |
Gene Type | protein-coding |
Description | KIAA0319 |
Other Description | dyslexia susceptibility 2|dyslexia-associated protein KIAA0319|neuronal migration |
Swissprots | Q5VV43 B2RTU7 F5H123 Q9Y4G7 B4DHA7 B7ZML3 Q9UJC8 B4DK75 A7MD37 |
Accessions | CCQ43461 EAW55455 EAW55456 EAW55457 Q5VV43 AB002317 BAA20777 AF086065 AK295008 BAG58068 AK296310 BAG59008 AK296426 BAG59087 AK307503 AK310289 AL044313 BC140821 AAI40822 BC144628 AAI44629 BC152460 AAI52461 BX646625 DA316925 DA808234 XM_006715288 XP_006715351 XM_011515022 XP_011513324 XM_011515023 XP_011513325 XM_011515024 XP_011513326 XM_011515025 XP_011513327 XM_011515026 XP_011513328 XM_011515027 XP_011513329 NM_001168374 NP_001161846 NM_001168375 NP_001161847 NM_001168376 NP_001161848 NM_001168377 NP_001161849 NM_001252328 NP_001239257 NM_014809 NP_055624 |
Function | Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non- cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites. {ECO:0000269|PubMed:19679544}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Note=Low-abundance isoforms lacking the transmembrane domain have been described; these are secreted. |
Tissue Specificity | Detected in adult brain cortex and fetal frontal lobe (at protein level). Highly expressed in brain cortex, putamen, amygdala, hippocampus and cerebellum. {ECO:0000269|PubMed:12834540, ECO:0000269|PubMed:17846832}. |
DYX2 (E-15) - sc-167706 from Santa Cruz Biotechnology
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DYX2 (S-21) - sc-133526 from Santa Cruz Biotechnology
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Anti-KIAA0319 Antibody (aa391-403) - LS-C87205 from LifeSpan Bioscience
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Anti-KIAA0319 Antibody (aa151-200) - LS-C80992 from LifeSpan Bioscience
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Anti-KIAA0319 Antibody (aa828-840) IHC-plus⢠- LS-B10287 from LifeSpan Bioscience
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KIAA0319 Antibody - NBP1-59471 from Novus Biologicals
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KIAA0319 Antibody - NBP1-86455 from Novus Biologicals
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DYX2/KIAA0319 Polyclonal Antibody - bs-11862R from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11862R-A350 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11862R-A488 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11862R-A555 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11862R-A647 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, Cy3 Conjugated - bs-11862R-Cy3 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, Cy5 Conjugated - bs-11862R-Cy5 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, Cy5.5 Conjugated - bs-11862R-Cy5.5 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, Cy7 Conjugated - bs-11862R-Cy7 from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, FITC Conjugated - bs-11862R-FITC from Bioss
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Rabbit Anti-DYX2/KIAA0319 Polyclonal Antibody, PE Conjugated - bs-11862R-PE from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, Biotin Conjugated - bs-11862R-Biotin from Bioss
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DYX2/KIAA0319 Polyclonal Antibody, HRP Conjugated - bs-11862R-HRP from Bioss
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Anti-KIAA0319 antibody produced in rabbit - HPA015607 from Sigma-Aldrich
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Anti-KIAA0319 antibody produced in rabbit - AV47083 from Sigma-Aldrich
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KIAA0319 antibody - N-terminal region (ARP47083_T100) - ARP47083_T100 from Aviva Systems Biology
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KIAA0319-Antibody-internal-region - AF2482a from Abgent, a WuXi AppTec company
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KIAA0319 Antibody - internal region (OAEB02542) - OAEB02542 from Aviva Systems Biology
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