Gene Symbol | GATAD2B |
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Entrez Gene | 57459 |
Alt Symbol | MRD18, P66beta, p68 |
Species | Human |
Gene Type | protein-coding |
Description | GATA zinc finger domain containing 2B |
Other Description | GATA zinc finger domain-containing protein 2B|p66/p68|transcription repressor p66 beta component of the MeCP1 complex|transcriptional repressor p66-beta |
Swissprots | Q7LG68 Q5VUR2 Q8WXI9 D3DUZ2 Q9ULS0 |
Accessions | EAW53270 Q8WXI9 AB032976 BAA86464 AF411836 AAL39080 AI701819 AK094665 BAG52906 BC069419 AAH69419 BC112052 AAI12053 BC112080 AAI12081 DA161156 EU446499 ABZ92028 XM_005245364 XP_005245421 XM_006711469 XP_006711532 XM_011509808 XP_011508110 NM_020699 NP_065750 |
Function | Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development. {ECO:0000269|PubMed:12183469, ECO:0000269|PubMed:16415179}. |
Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:11756549, ECO:0000269|PubMed:12183469, ECO:0000269|PubMed:16415179}. Note=Speckled nuclear localization requires both CR1 and CR2 regions. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12183469}. |
Human p66 beta protein fragment - ab153450 from Abcam
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GATAD2B Antibody Blocking Peptide - LS-E3341 from LifeSpan Bioscience
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GATAD2B Antibody Blocking Peptide - LS-E14249 from LifeSpan Bioscience
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GATAD2B Antibody Blocking Peptide - LS-E14248 from LifeSpan Bioscience
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GATAD2B Antibody Blocking Peptide - LS-E11601 from LifeSpan Bioscience
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GATAD2B Antibody Blocking Peptide - LS-E11602 from LifeSpan Bioscience
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Recombinant Human p66 beta Protein - H00057459-Q01 from Novus Biologicals
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GATAD2B-Antibody-N-term-Blocking-Peptide - BP14510a from Abgent, a WuXi AppTec company
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GATAD2B / Hp66 beta - H00057459-Q01-10 from Acris Antibodies
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GATAD2B / Hp66 beta - H00057459-Q01-25 from Acris Antibodies
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GATAD2B fusion protein - Ag22615 from Proteintech Group
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Recombinant Human Transcriptional repressor p66-beta(GATAD2B) - CSB-YP823905HU CSB-EP823905HU CSB-BP823905HU CSB-MP823905HU from Cusabio
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p66 beta Recombinant Protein Antigen - NBP1-87358PEP from Novus Biologicals
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GATAD2B Peptide, Human - M34GP06128H from Creative Peptides
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