Gene Symbol | CRB1 |
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Entrez Gene | 23418 |
Alt Symbol | LCA8, RP12 |
Species | Human |
Gene Type | protein-coding |
Description | crumbs family member 1, photoreceptor morphogenesis associated |
Other Description | protein crumbs homolog 1 |
Swissprots | Q5VUT1 Q8WWY0 Q6N027 A2A308 P82279 Q5TC28 B7Z5T2 Q5K3A6 Q8WWY1 B9EG71 |
Accessions | CCQ43949 EAW91277 P82279 AB208923 BAD92160 AF154671 AAF01361 AJ748821 CAG38658 AK289733 BAF82422 AK299367 BAH13017 AK299368 BAH13018 AK302818 BAH13810 AK302826 BAH13812 AK307844 AY043322 AY043323 AAL10680 AY043324 AAL10681 AY043325 AAL10682 BC136271 AAI36272 BC143726 BX640729 CAE45845 DC370545 DC370777 XM_011509365 XP_011507667 XM_011509366 XP_011507668 XM_011509367 XP_011507669 XM_011509368 XP_011507670 XM_011509369 XP_011507671 NM_001193640 NP_001180569 NM_001257965 NP_001244894 NM_001257966 NP_001244895 NM_201253 NP_957705 NR_047563 NR_047564 NM_012076 |
Function | Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion. |
Subcellular Location | Isoform 1: Apical cell membrane; Single-pass type I membrane protein. Note=Distributed at the apical membrane of all retinal epithelial cells. Located in the apical membrane of the adherens junction in outer limiting membrane (OLM) of the retina. |
Tissue Specificity | Preferential expression in retina, also expressed in brain, testis, fetal brain and fetal eye. {ECO:0000269|PubMed:15914641}. |
Top Pathways | Hippo signaling pathway |
CRB1 (H-14) - sc-22738 from Santa Cruz Biotechnology
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Anti-CRB1 antibody - ab156282 from Abcam
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Anti-CRB1 Antibody (Internal) IHC-plus™ - LS-B10066 from LifeSpan Bioscience
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CRB1 Antibody - H00023418-A01 from Novus Biologicals
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Anti-CRB1 antibody produced in rabbit - SAB3500788 from Sigma-Aldrich
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CRB1 antibody - orb179047 from Biorbyt
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Anti -CRB1 (Cellular Retinol-binding Protein I) - 215591 from USBiological Life Science
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Crumbs homolog 1 antibody - H00023418-A01 from Acris Antibodies
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CRB1 Antibody - 7153 from ProSci
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CRB1, Polyclonal Antibody - MBS153460 from MyBioSource
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CRB1, Polyclonal Antibody - MBS248274 from MyBioSource
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Anti-CRB1 (aa 26-134) polyclonal antibody - DPAB-DC1098 from Creative Diagnostics
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Anti-CRB1 polyclonal antibody - DPABH-05628 from Creative Diagnostics
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CRB1 Polyclonal Antibody - PA5-34491 from Thermo Fisher Scientific
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CRB1 Antibody - 600-401-AM9 from Rockland Immunochemicals Inc
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CRB1 (Internal) antibody - pab76352 from Covalab
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Anti-CRB1-Antibody-Internal-ALS16003 - ALS16003 from Abgent, a WuXi AppTec company
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CRB1 Antibody - NBP2-41201 from Novus Biologicals
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CRB1 antibody - GTX32103 from GeneTex
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CRB1 antibody - pab81557 from Covalab
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CRB1-Antibody - ASC11589 from Abgent, a WuXi AppTec company
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Crumbs homolog 1 antibody - TA319859 from Acris Antibodies
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CRB1 Antibody - CSB-PA005941DSR1HU from Cusabio
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Anti-CRB1 Antibody, clone 1C2.1 - MABN1572 from EMD Millipore
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CRB1 Antibody - NBP2-56113 from Novus Biologicals
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