CRB1

Gene Symbol CRB1
Entrez Gene 23418
Alt Symbol LCA8, RP12
Species Human
Gene Type protein-coding
Description crumbs family member 1, photoreceptor morphogenesis associated
Other Description protein crumbs homolog 1
Swissprots Q5VUT1 Q8WWY0 Q6N027 A2A308 P82279 Q5TC28 B7Z5T2 Q5K3A6 Q8WWY1 B9EG71
Accessions CCQ43949 EAW91277 P82279 AB208923 BAD92160 AF154671 AAF01361 AJ748821 CAG38658 AK289733 BAF82422 AK299367 BAH13017 AK299368 BAH13018 AK302818 BAH13810 AK302826 BAH13812 AK307844 AY043322 AY043323 AAL10680 AY043324 AAL10681 AY043325 AAL10682 BC136271 AAI36272 BC143726 BX640729 CAE45845 DC370545 DC370777 XM_011509365 XP_011507667 XM_011509366 XP_011507668 XM_011509367 XP_011507669 XM_011509368 XP_011507670 XM_011509369 XP_011507671 NM_001193640 NP_001180569 NM_001257965 NP_001244894 NM_001257966 NP_001244895 NM_201253 NP_957705 NR_047563 NR_047564 NM_012076
Function Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion.
Subcellular Location Isoform 1: Apical cell membrane; Single-pass type I membrane protein. Note=Distributed at the apical membrane of all retinal epithelial cells. Located in the apical membrane of the adherens junction in outer limiting membrane (OLM) of the retina.
Tissue Specificity Preferential expression in retina, also expressed in brain, testis, fetal brain and fetal eye. {ECO:0000269|PubMed:15914641}.
Top Pathways Hippo signaling pathway

CRB1 CRISPR/Cas9 KO Plasmid (h) - sc-418097 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 HDR Plasmid (h) - sc-418097-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 Double Nickase Plasmid (h) - sc-418097-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 Double Nickase Plasmid (h2) - sc-418097-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 CRISPR Activation Plasmid (h) - sc-418097-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 CRISPR Activation Plasmid (h2) - sc-418097-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 Lentiviral Activation Particles (h) - sc-418097-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 Lentiviral Activation Particles (h2) - sc-418097-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRB1 siRNA (h) - sc-44481 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRB1 shRNA Plasmid (h) - sc-44481-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRB1 shRNA (h) Lentiviral Particles - sc-44481-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRB1 RNAi - H00023418-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CRB1 RNAi - H00023418-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU066171 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6545 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6545 from Sigma-Aldrich

Category ZFN Kit
Prices $4,120.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04764 from Sigma-Aldrich

Category miRNA

CRB1 siRNA (Human) - CRH8257 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRB1 - MBS8202608 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CRB1 (NM_201253.2) - SHH269201 from Creative biogene

Category siRNA
Species Reactivities Human

Human CRB1 siRNA - orb268759 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRB1 shRNA Plasmid (Human) - CHH8257 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CRB1 miRNA 3'UTR clone - MiUTR3H-06645 from Creative biogene

Species Reactivities Human
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