CRB1

Gene Symbol	CRB1
Entrez Gene	23418
Alt Symbol	LCA8, RP12
Species	Human
Gene Type	protein-coding
Description	crumbs family member 1, photoreceptor morphogenesis associated
Other Description	protein crumbs homolog 1
Swissprots	Q5VUT1 Q8WWY0 Q6N027 A2A308 P82279 Q5TC28 B7Z5T2 Q5K3A6 Q8WWY1 B9EG71
Accessions	CCQ43949 EAW91277 P82279 AB208923 BAD92160 AF154671 AAF01361 AJ748821 CAG38658 AK289733 BAF82422 AK299367 BAH13017 AK299368 BAH13018 AK302818 BAH13810 AK302826 BAH13812 AK307844 AY043322 AY043323 AAL10680 AY043324 AAL10681 AY043325 AAL10682 BC136271 AAI36272 BC143726 BX640729 CAE45845 DC370545 DC370777 XM_011509365 XP_011507667 XM_011509366 XP_011507668 XM_011509367 XP_011507669 XM_011509368 XP_011507670 XM_011509369 XP_011507671 NM_001193640 NP_001180569 NM_001257965 NP_001244894 NM_001257966 NP_001244895 NM_201253 NP_957705 NR_047563 NR_047564 NM_012076
Function	Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion.
Subcellular Location	Isoform 1: Apical cell membrane; Single-pass type I membrane protein. Note=Distributed at the apical membrane of all retinal epithelial cells. Located in the apical membrane of the adherens junction in outer limiting membrane (OLM) of the retina.
Tissue Specificity	Preferential expression in retina, also expressed in brain, testis, fetal brain and fetal eye. {ECO:0000269|PubMed:15914641}.
Top Pathways	Hippo signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CRB1 protein fragment - ab161634 from Abcam Category Protein Source Wheat germ Species Human

CRB1 Antibody Blocking Peptide - LS-E31374 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human CRB1 Protein - H00023418-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Crumbs homolog 1 - H00023418-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Crumbs homolog 1 - H00023418-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CRB1 Peptide - 7153P from ProSci Category Peptide Species Human

CRB1 fusion protein - ag19920 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Crumbs homolog 1(CRB1) ,partial - CSB-YP005941HU CSB-EP005941HU CSB-BP005941HU CSB-MP005941HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CRB1 Peptide, Human - M34GP03613H from Creative Peptides Category Peptide Source Synthetic. Species Human

CRB1 Recombinant Protein Antigen - NBP2-55734PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CRB1 Recombinant Protein Antigen - NBP2-56113PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Crumbs homolog 1 (CRB1), partial, Recombinant Protein - MBS963270 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CRB1 fusion protein - Ag24139 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

CRB1 fusion protein - Ag24512 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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