PIK3C2B

Gene Symbol	PIK3C2B
Entrez Gene	5287
Alt Symbol	C2-PI3K
Species	Human
Gene Type	protein-coding
Description	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
Other Description	PI3K-C2-beta|PI3K-C2beta|PTDINS-3-kinase C2 beta|phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide|phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta|phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta|phosphoinositide 3-kinase-C2-beta|phosphoinositide-3-kinase, class 2, beta polypeptide|ptdIns-3-kinase C2 subunit beta
Swissprots	Q5SW99 O00750 O95666
Accessions	ABY87552 AGC09602 EAW91513 EAW91514 O00750 AB210006 BAE06088 AK308153 BC094741 BC132876 AAI32877 BC136645 AAI36646 BC144342 AAI44343 CR749201 CAH18059 F17716 Y11312 CAA72168 Y13892 CAA74194 XM_005245257 XP_005245314 XM_005245258 XP_005245315 XM_011509630 XP_011507932 XM_011509631 XP_011507933 XM_011509632 XP_011507934 XM_011509633 XP_011507935 XR_241085 XR_241086 NM_002646 NP_002637
Function	Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involved in EGF and PDGF signaling cascades. {ECO:0000269|PubMed:10805725}.
Subcellular Location	Microsome {ECO:0000269|PubMed:14563213}. Cell membrane {ECO:0000269|PubMed:14563213}. Cytoplasm, cytosol {ECO:0000269|PubMed:14563213}. Nucleus {ECO:0000269|PubMed:14563213}. Endoplasmic reticulum {ECO:0000269|PubMed:14563213}. Note=Found mostly in the microsome, but also in the plasma membrane and cytosol. Nuclear in testis.
Tissue Specificity	Expressed in columnar and transitional epithelia, mononuclear cells, and ganglion cells (at protein level). Widely expressed, with highest levels in thymus and placenta and lowest in peripheral blood, skeletal muscle and kidney. {ECO:0000269|PubMed:14563213, ECO:0000269|PubMed:9144573}.
Top Pathways	Inositol phosphate metabolism, Phosphatidylinositol signaling system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PI 3-kinase C2β (C-14) - sc-48630 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

PI 3-kinase C2γ (M-228) - sc-134768 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

PI 3-kinase C2β (16L9) - sc-100407 from Santa Cruz Biotechnology Prices $295.00 Sizes 50 µg/0.5 ml Host Mouse Clonality Monoclonal

PI 3-kinase C2β (22) - sc-136031 from Santa Cruz Biotechnology Prices $279.00 Sizes 50 µg/0.5 ml Host Mouse Clonality Monoclonal

Anti-PIK3C2B antibody - ab55589 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-PIK3C2B antibody [2G3] - ab140525 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2G3

Anti-PIK3C2B Antibody (clone 3B1) - LS-C174656 from LifeSpan Bioscience Prices $325.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 3B1

Anti-PIK3C2B Antibody (N-Terminus, AP) - LS-C220361 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (N-Terminus, APC) - LS-C220363 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (N-Terminus, Biotin) - LS-C220364 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (N-Terminus, FITC) - LS-C220365 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (N-Terminus, Azide-free, HRP) - LS-C220366 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (N-Terminus, PE) - LS-C220367 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (clone 1H4) - LS-C139415 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1H4

Anti-PIK3C2B Antibody (aa120-150) - LS-C99827 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (aa790-1025, Biotin) - LS-C297590 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (aa790-1025, FITC) - LS-C304135 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (N-Terminus) - LS-C328242 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (aa1584-1634) - LS-C290914 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (aa790-1025) - LS-C295901 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (Tyr228) - LS-C344671 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-PIK3C2B Antibody (clone 2G3) - LS-C174638 from LifeSpan Bioscience Prices $350.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 2G3

PI 3-Kinase C2 beta Antibody - AF7249 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

PI 3-Kinase C2 beta Antibody (3E5.) - H00005287-M02 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3E5.

PI 3-Kinase C2 beta Antibody (1H4) - H00005287-M06 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1H4

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