Gene Symbol | NOP2 |
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Entrez Gene | 4839 |
Alt Symbol | NOL1, NOP120, NSUN1, p120 |
Species | Human |
Gene Type | protein-coding |
Description | NOP2 nucleolar protein |
Other Description | NOL1/NOP2/Sun domain family, member 1|NOP2 nucleolar protein homolog|nucleolar protein 1, 120kDa|nucleolar protein 2 homolog|probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase|proliferating-cell nucleolar antigen p120|proliferation-associated nucleolar protein p120|putative ribosomal RNA methyltransferase NOP2 |
Swissprots | Q58F30 Q3KQS4 Q05BA7 A1A4Z3 P46087 Q0P5S5 B3KPD6 |
Accessions | EAW88780 P46087 AK056208 BAG51648 AK129852 AK307582 AU131299 BC000656 AAH00656 BC065257 AAH65257 BC082985 AAH82985 BC106072 AAI06073 BC128183 AAI28184 BC128184 AAI28185 CX868076 DC316656 M32110 AAA36398 X55504 CAA39119 XM_005253691 XP_005253748 XM_011520962 XP_011519264 NM_001033714 NP_001028886 NM_001258308 NP_001245237 NM_001258309 NP_001245238 NM_001258310 NP_001245239 NM_006170 NP_006161 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. {ECO:0000305}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
NSUN1 (E-7) - sc-398884 from Santa Cruz Biotechnology
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NSUN1 (E-20) - sc-83439 from Santa Cruz Biotechnology
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NSUN1 (G-16) - sc-83440 from Santa Cruz Biotechnology
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NSUN1 (H-149) - sc-292098 from Santa Cruz Biotechnology
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Anti-NOP2 antibody - N-terminal - ab135374 from Abcam
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Anti-Proliferation Associated Nucleolar Antigen antibody - ab86094 from Abcam
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NOL1 Antibody - NBP1-92192 from Novus Biologicals
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NOL1 Antibody - NBP1-18907 from Novus Biologicals
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NOL1 Polyclonal Antibody - bs-9710R from Bioss
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Anti-NOP2 antibody produced in rabbit - HPA040119 from Sigma-Aldrich
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Anti-NOP2 (2-15) antibody produced in rabbit - SAB1104512 from Sigma-Aldrich
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NSUN1 antibody [N2C2], Internal - GTX105945 from GeneTex
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Nucleolar Antigen antibody [B462] - GTX72168 from GeneTex
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NOP2 antibody - 70R-18922 from Fitzgerald
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NOP2 antibody - 10448-1-AP from Acris Antibodies
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Anti-NSUN5, Polyclonal Antibody - 25-A5992 from ARP American Research Products
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NOP2 antibody - 10448-1-AP from Proteintech Group
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p120 ctn, Monoclonal Antibody - MBS603684 from MyBioSource
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NOP2 - A5878 from NeoScientific
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NSUN1 Antibody - 35431 from Signalway Antibody
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Anti-NOP2 (aa 8-57) polyclonal antibody - DPABH-26034 from Creative Diagnostics
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NOL1 Antibody - A302-018A from Bethyl Labs
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NOP2 Polyclonal Antibody - PA5-34712 from Thermo Fisher Scientific
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NOP2/Sun Domain Family, Polyclonal Antibody - MBS280084 from MyBioSource
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NSUN1 - MBS274950 from MyBioSource
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