Gene Symbol | NOP2 |
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Entrez Gene | 4839 |
Alt Symbol | NOL1, NOP120, NSUN1, p120 |
Species | Human |
Gene Type | protein-coding |
Description | NOP2 nucleolar protein |
Other Description | NOL1/NOP2/Sun domain family, member 1|NOP2 nucleolar protein homolog|nucleolar protein 1, 120kDa|nucleolar protein 2 homolog|probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase|proliferating-cell nucleolar antigen p120|proliferation-associated nucleolar protein p120|putative ribosomal RNA methyltransferase NOP2 |
Swissprots | Q58F30 Q3KQS4 Q05BA7 A1A4Z3 P46087 Q0P5S5 B3KPD6 |
Accessions | EAW88780 P46087 AK056208 BAG51648 AK129852 AK307582 AU131299 BC000656 AAH00656 BC065257 AAH65257 BC082985 AAH82985 BC106072 AAI06073 BC128183 AAI28184 BC128184 AAI28185 CX868076 DC316656 M32110 AAA36398 X55504 CAA39119 XM_005253691 XP_005253748 XM_011520962 XP_011519264 NM_001033714 NP_001028886 NM_001258308 NP_001245237 NM_001258309 NP_001245238 NM_001258310 NP_001245239 NM_006170 NP_006161 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. {ECO:0000305}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
NSUN1 CRISPR/Cas9 KO Plasmid (h) - sc-409656 from Santa Cruz Biotechnology
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NSUN1 HDR Plasmid (h) - sc-409656-HDR from Santa Cruz Biotechnology
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NSUN1 Double Nickase Plasmid (h) - sc-409656-NIC from Santa Cruz Biotechnology
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NSUN1 Double Nickase Plasmid (h2) - sc-409656-NIC-2 from Santa Cruz Biotechnology
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NSUN1 CRISPR Activation Plasmid (h) - sc-409656-ACT from Santa Cruz Biotechnology
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NSUN1 CRISPR Activation Plasmid (h2) - sc-409656-ACT-2 from Santa Cruz Biotechnology
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NSUN1 Lentiviral Activation Particles (h) - sc-409656-LAC from Santa Cruz Biotechnology
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NSUN1 Lentiviral Activation Particles (h2) - sc-409656-LAC-2 from Santa Cruz Biotechnology
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NSUN1 siRNA (h) - sc-75962 from Santa Cruz Biotechnology
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NSUN1 shRNA Plasmid (h) - sc-75962-SH from Santa Cruz Biotechnology
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NSUN1 shRNA (h) Lentiviral Particles - sc-75962-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU054681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15414 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15414 from Sigma-Aldrich
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NOP2 siRNA (Human) - CRH3215 from Cohesion Biosciences
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shRNA set against Human NOP2 (NM_006170.3) - SHH353696 from Creative biogene
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Human NOP2 siRNA - orb263717 from Biorbyt
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NOP2 shRNA Plasmid (Human) - CHH3215 from Cohesion Biosciences
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NOP2 miRNA 3'UTR clone - MiUTR3H-01573 from Creative biogene
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NOP2 miRNA 3'UTR clone - MiUTR3H-01574 from Creative biogene
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