Gene Symbol |
NOP2
|
Entrez Gene |
4839
|
Alt Symbol |
NOL1, NOP120, NSUN1, p120
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NOP2 nucleolar protein
|
Other Description |
NOL1/NOP2/Sun domain family, member 1|NOP2 nucleolar protein homolog|nucleolar protein 1, 120kDa|nucleolar protein 2 homolog|probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase|proliferating-cell nucleolar antigen p120|proliferation-associated nucleolar protein p120|putative ribosomal RNA methyltransferase NOP2
|
Swissprots |
Q58F30 Q3KQS4 Q05BA7 A1A4Z3 P46087 Q0P5S5 B3KPD6
|
Accessions |
EAW88780 P46087 AK056208 BAG51648 AK129852 AK307582 AU131299 BC000656 AAH00656 BC065257 AAH65257 BC082985 AAH82985 BC106072 AAI06073 BC128183 AAI28184 BC128184 AAI28185 CX868076 DC316656 M32110 AAA36398 X55504 CAA39119 XM_005253691 XP_005253748 XM_011520962 XP_011519264 NM_001033714 NP_001028886 NM_001258308 NP_001245237 NM_001258309 NP_001245238 NM_001258310 NP_001245239 NM_006170 NP_006161
|
Function |
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. {ECO:0000305}.
|
Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:12429849}.
|