Gene Symbol | RAB20 |
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Entrez Gene | 55647 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAB20, member RAS oncogene family |
Other Description | ras-related protein Rab-20 |
Swissprots | Q5T9X5 Q9NX57 Q9NX49 |
Accessions | EAX09113 Q9NX57 AJ272065 CAC81247 AK000436 BAA91163 AK000446 BAA91171 BC026025 AAH26025 BU528103 DQ892145 ABM83071 DQ895340 ABM86266 HY010547 NM_017817 NP_060287 |
Function | Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. {ECO:0000269|PubMed:21255211}. |
Subcellular Location | Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis. {ECO:0000250}. |
Tissue Specificity | Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level). {ECO:0000269|PubMed:16613320}. |
Rab 20 CRISPR/Cas9 KO Plasmid (h) - sc-412563 from Santa Cruz Biotechnology
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Rab 20 HDR Plasmid (h) - sc-412563-HDR from Santa Cruz Biotechnology
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Rab 20 Double Nickase Plasmid (h) - sc-412563-NIC from Santa Cruz Biotechnology
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Rab 20 Double Nickase Plasmid (h2) - sc-412563-NIC-2 from Santa Cruz Biotechnology
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Rab 20 CRISPR Activation Plasmid (h) - sc-412563-ACT from Santa Cruz Biotechnology
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Rab 20 CRISPR Activation Plasmid (h2) - sc-412563-ACT-2 from Santa Cruz Biotechnology
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Rab 20 Lentiviral Activation Particles (h) - sc-412563-LAC from Santa Cruz Biotechnology
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Rab 20 Lentiviral Activation Particles (h2) - sc-412563-LAC-2 from Santa Cruz Biotechnology
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Rab 20 siRNA (h) - sc-76320 from Santa Cruz Biotechnology
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Rab 20 shRNA Plasmid (h) - sc-76320-SH from Santa Cruz Biotechnology
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Rab 20 shRNA (h) Lentiviral Particles - sc-76320-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU043041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17818 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17818 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04768 from Sigma-Aldrich
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RAB20 siRNA (Human) - CRJ0801 from Cohesion Biosciences
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RAB20 - MBS8210406 from MyBioSource
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shRNA set against Human RAB20 (NM_017817.1) - SHH388016 from Creative biogene
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shRNA set against Human RAB20(NM_017817.1) - SHR158268 from Creative biogene
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RAB20 shRNA Plasmid (Human) - CHJ0801 from Cohesion Biosciences
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RAB20 miRNA 3'UTR clone - MiUTR1H-08545 from Creative biogene
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